C60 fullerene enhances cisplatin anticancer activity and overcomes tumor cell drug resistance

We formulated and analyzed a novel nanoformulation of the anticancer drug cisplatin （Cis） with C60 fullerene （C60＋Cis complex） and showed its higher toxicity toward tumor cell lines in vitro when compared to Cis alone. The highest toxicity of the complex was observed in HL-60/adr and HL-60/vinc chem...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nano research 2017-02, Vol.10 (2), p.652-671
Hauptverfasser:	Prylutska, Svitlana, Panchuk, Rostyslav, Gołuński, Grzegorz, Skivka, Larysa, Prylutskyy, Yuriy, Hurmach, Vasyl, Skorohyd, Nadya, Borowik, Agnieszka, Woziwodzka, Anna, Piosik, Jacek, Kyzyma, Olena, Garamus, Vasil, Bulavin, Leonid, Evstigneev, Maxim, Buchelnikov, Anatoly, Stoika, Rostyslav, Berger, Walter, Ritter, Uwe, Scharff, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Ames test Annexin V Anticancer properties Antitumor activity Apoptosis Atomic/Molecular Structure and Spectra Binding sites Biocompatibility Biomedicine Biotechnology Buckminsterfullerene Cancer Cell death Chemistry and Materials Science Chemotherapy Cisplatin Condensed Matter Physics Drug resistance Fullerenes Glycoproteins In vivo methods and tests Leukemia Lung cancer Lung carcinoma Material requirements planning Materials Science Molecular docking MRP1 protein Multidrug resistance Nanotechnology Neoplasia P-Glycoprotein Research Article Toxicity Tumor cell lines Tumors Vinculin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!