Integrating genome‐wide association study summaries and element‐gene interaction datasets identified multiple associations between elements and complex diseases

ABSTRACT Chemical elements are closely related to human health. Extensive genomic profile data of complex diseases offer us a good opportunity to systemically investigate the relationships between elements and complex diseases/traits. In this study, we applied gene set enrichment analysis (GSEA) app...

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Veröffentlicht in:	Genetic epidemiology 2018-03, Vol.42 (2), p.168-173
Hauptverfasser:	He, Awen, Wang, Wenyu, Prakash, N. Tejo, Tinkov, Alexey A., Skalny, Anatoly V., Wen, Yan, Hao, Jingcan, Guo, Xiong, Zhang, Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Aluminum Alzheimer's disease Bipolar disorder Bone mineral density Calcium Chemical elements complex diseases Datasets elements Gene set enrichment analysis Genome-wide association studies Genomes Hypertriglyceridemia Magnesium Neurodegenerative diseases Nickel Systemic lupus erythematosus
Online-Zugang:	Volltext
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