Single‐tube library preparation for degraded DNA

In recent years, massive parallel sequencing has revolutionised the study of degraded DNA, thus enabling the field of ancient DNA to evolve into that of paleogenomics. Despite these advances, the recovery and sequencing of degraded DNA remains challenging due to limitations in the manipulation of ch...

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Veröffentlicht in:	Methods in ecology and evolution 2018-02, Vol.9 (2), p.410-419
Hauptverfasser:	Carøe, Christian, Gopalakrishnan, Shyam, Vinner, Lasse, Mak, Sarah S. T., Sinding, Mikkel Holger S., Samaniego, José A., Wales, Nathan, Sicheritz‐Pontén, Thomas, Gilbert, M. Thomas P., Johnston, Susan
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological evolution Chemical damage Costs Degradation degraded DNA Deoxyribonucleic acid DNA DNA sequencing Downstream effects Genomes illumina sequencing Libraries library preparation museomics paleogenomics Purification Studies
Online-Zugang:	Volltext
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