Within-Subject Variability and Boosting of T-Cell Interferon-{gamma} Responses after Tuberculin Skin Testing

The optimal strategy for the diagnosis of latent tuberculosis infection is controversial. Adoption of a two-step strategy (tuberculin skin test [TST] followed by an IFN-gamma release assay [IGRA], compared with an IGRA alone), may be limited by TST-mediated boosting of subsequent IGRA responses. Ass...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2009-07, Vol.180 (1), p.49
Hauptverfasser:	van Zyl-Smit, Richard N, Pai, Madhukar, Peprah, Kwaku, Meldau, Richard, Kieck, Jackie, Juritz, June, Badri, Motasim, Zumla, Alimuddin, Sechi, Leonardo A, Bateman, Eric D, Dheda, Keertan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Health care Infections Medical personnel Medical students Thoracic surgery Tuberculosis
Online-Zugang:	Volltext
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