Molecular Docking Studies of Medicinal Compounds against Aldose reductase Drug Target for Treatment of Type 2 Diabetes

Type 2 Diabetes is a disease that manifests from combined effect of genetic and environmental stress on multiple tissues over a period of time. An enzyme, Aldose Reductase play an important role in oxidative stress and Diabetic Mellitus was selected as a target protein for in silico screening of sui...

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Veröffentlicht in:	International Journal of Bioinformatics and Biological Sciences 2017-12, Vol.5 (2), p.91-116
Hauptverfasser:	Singh, Pratistha, Yadav, Preeti, Singh, V.K., Singh, A.K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehyde reductase Binding sites Cardiovascular disease Coumarin Developing countries Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Disease control Disease prevention Drug therapy Environmental stress Enzymes Glucose Herbal medicine Inositol Insulin resistance Kidney diseases LDCs Ligands Metabolism Molecular biology Molecular docking Oxidative stress Quercetin Rodents Tolbutamide
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