A novel herbal beverage from Moringa oleifera, Dennettia tripetala, and Citrus sinensis abates Bonny light crude oil-induced oxidative injury in rat brain and liver

A novel herbal beverage from Moringa oleifera, Dennettia tripetala, and Citrus sinensis abates Bonny light crude oil-induced oxidative injury in rat brain and liver

A novel herbal beverage (HB) was formulated from blends of Moringa oleifera , Dennettia tripetala , and Citrus sinensis and investigated for its antioxidative protective effect against Bonny light crude oil (BLCO)-induced oxidative injury in rat brain and hepatic tissues. Male albino rats were orall...

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Veröffentlicht in:Comparative clinical pathology 2018-05, Vol.27 (3), p.699-704
Hauptverfasser: Ebuehi, Osaretin A. T., Erukainure, Ochuko L., Adione, Rebecca, Oyenihi, Ayodeji B.
Format: Artikel
Sprache:eng
Schlagworte:
Alanine transaminase
Alkaline phosphatase
Aspartate aminotransferase
Bilirubin
Brain injury
Citrus sinensis
Crude oil
Dennettia tripetala
Hematology
Light effects
Liver
Malondialdehyde
Medicine
Medicine & Public Health
Moringa oleifera
Oncology
Original Article
Oxidation
Pathology
Quercetin
Rodents
Superoxide dismutase
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Beschreibung
Zusammenfassung:A novel herbal beverage (HB) was formulated from blends of Moringa oleifera , Dennettia tripetala , and Citrus sinensis and investigated for its antioxidative protective effect against Bonny light crude oil (BLCO)-induced oxidative injury in rat brain and hepatic tissues. Male albino rats were orally exposed to BLCO (800 mg/kg bodyweight) for 7 days, then treated with HB (200 and 400 mg/kg bodyweight) for another 7 days. Reduced glutathione (GSH) and malondialdehyde (MDA) levels were depleted and elevated respectively in both tissues on exposure to BLCO, which was ( p  
ISSN:1618-5641
1618-565X
DOI:10.1007/s00580-018-2654-0