Pulmonary Toxicity of Benzalkonium Chloride

The available toxicity data of benzalkonium chloride (BKC) clearly shows that it is toxic; however, the weight of evidence favors the view that at doses encountered in nasally and orally inhaled pharmaceutical preparations it is well tolerated. The adverse toxicological data predominantly come from...

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Veröffentlicht in:	Journal of aerosol medicine 2018-02, Vol.31 (1), p.1-17
1. Verfasser:	Johnson, Neil F
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Alcohol Animals Antimicrobial agents Asthma Benzalkonium chloride Benzalkonium Compounds - administration & dosage Benzalkonium Compounds - toxicity Chloride Chlorides Cornea Cytotoxicity Humans Microenvironments Nasal Mucosa - metabolism Physicochemical properties Polyamines Preservatives, Pharmaceutical - administration & dosage Preservatives, Pharmaceutical - toxicity Proteins Respiratory System - drug effects Respiratory System - metabolism Respiratory tract Studies Toxicity Toxicology
Online-Zugang:	Volltext
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