Genotoxicity of carbon tetrachloride and the protective role of essential oil of Salvia officinalis L. in mice using chromosomal aberration, micronuclei formation, and comet assay

The present work was conducted to evaluate the genotoxic effect of carbon tetrachloride (CCl 4 ) in mouse bone marrow and male germ cells. The safety and the modulating activity of sage ( Salvia officinalis L.) essential oil (SEO) against the possible genotoxic effect of CCl 4 were also evaluated. A...

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Veröffentlicht in:	Environmental science and pollution research international 2018, Vol.25 (2), p.1621-1636
Hauptverfasser:	Diab, Kawthar AE, Fahmy, Maha A., Hassan, Zeinab M., Hassan, Emad M., Salama, Adel B., Omara, Enayat A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Abnormalities Acridine orange Apoptosis Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Bioassays Bone marrow Carbon tetrachloride Chromosome aberrations Comet assay Damage detection Deoxyribonucleic acid DNA DNA damage Earth and Environmental Science Ecotoxicology Environment Environmental Chemistry Environmental Health Environmental science Essential oils Ethidium bromide Gas chromatography Genotoxicity Germ cells Mass spectrometry Mass spectroscopy Mice Micronuclei Oils & fats Research Article Safety Salvia officinalis Sperm Spermatocytes Testes Waste Water Technology Water Management Water Pollution Control
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