Photoautotrophic production of macular pigment in a Chlamydomonas reinhardtii strain generated by using DNA‐free CRISPR‐Cas9 RNP‐mediated mutagenesis

Lutein and zeaxanthin are dietary carotenoids reported to be protective against age‐related macular degeneration. Recently, the green alga Chlamydomonas reinhardtii has received attention as a photosynthetic cell factory, but the potential of this alga for carotenoid production has not yet been eval...

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Veröffentlicht in:	Biotechnology and bioengineering 2018-03, Vol.115 (3), p.719-728
Hauptverfasser:	Baek, Kwangryul, Yu, Jihyeon, Jeong, Jooyeon, Sim, Sang Jun, Bae, Sangsu, Jin, EonSeon
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Algae algal biotechnology Biotechnology Carotenoids Chlamydomonas reinhardtii Chlorophyll CRISPR CRISPR‐Cas9 Deoxyribonucleic acid Diet DNA Eggs Lutein Macular degeneration Mutagenesis Mutants Photosynthesis Ribonucleoproteins Zeaxanthin Zeaxanthin epoxidase
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