Promoter hypermethylation may contribute to E‑cadherin repression in the human salivary carcinoma ex pleomorphic adenoma

The role of promoter methylation in the inactivation of E‑cadherin (CDH1) in salivary carcinoma ex pleomorphic adenoma (CXPA) is unknown. The objective of this study was to determine the role and potential clinical implications of CDH1 promoter methylation in salivary CXPA. The CDH1 promoter methyla...

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Veröffentlicht in:	International journal of oncology 2018-02, Vol.52 (2), p.496-504
Hauptverfasser:	Xia, Liang, Hu, Yuhua, Gu, Ting, Wang, Lizhen, Tian, Zhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma Cadherins Cancer Care and treatment Cell adhesion & migration Deoxyribonucleic acid Development and progression DNA DNA methylation Epigenetics Gene expression Genetic aspects Health aspects Lymphatic system Medical prognosis Oral cancer Polymerase chain reaction Promoters (Genetics) Protein expression Tumors
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