Different roles of Akt and mechanistic target of rapamycin in serum‑dependent chondroprotection of human osteoarthritic chondrocytes

Despite various animal serums being used widely to culture chondrocytes, the regulatory mechanism of serum on chondrocyte activities has not been elucidated. In the present study, human osteoarthritis (OA) chondrocytes were used to perform in vitro investigations on the effect of different concentra...

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Veröffentlicht in:International journal of molecular medicine 2018-02, Vol.41 (2), p.977-984
Hauptverfasser: Zhang, Tongen, Liu, Jijie, Zheng, Xinpeng, Zhang, Bing, Xia, Chun
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Sprache:eng
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