Pharmacokinetics of Escalating Doses of Oral Psilocybin in Healthy Adults

Introduction Psilocybin is a psychedelic tryptamine that has shown promise in recent clinical trials for the treatment of depression and substance use disorders. This open-label study of the pharmacokinetics of psilocybin was performed to describe the pharmacokinetics and safety profile of psilocybi...

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Veröffentlicht in:	Clinical pharmacokinetics 2017-12, Vol.56 (12), p.1543-1554
Hauptverfasser:	Brown, Randall T., Nicholas, Christopher R., Cozzi, Nicholas V., Gassman, Michele C., Cooper, Karen M., Muller, Daniel, Thomas, Chantelle D., Hetzel, Scott J., Henriquez, Kelsey M., Ribaudo, Alexandra S., Hutson, Paul R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Chromatography, Liquid - methods Clinical trials Dose-Response Relationship, Drug Drug dosages FDA approval Female Glucuronides - pharmacokinetics Half-Life Hallucinogens - administration & dosage Hallucinogens - adverse effects Hallucinogens - pharmacokinetics Humans Internal Medicine Male Mass spectrometry Medicine Medicine & Public Health Methods Middle Aged Nonlinear Dynamics Original Research Article Pharmacokinetics Pharmacology/Toxicology Pharmacotherapy Population Psilocybin - administration & dosage Psilocybin - adverse effects Psilocybin - analogs & derivatives Psilocybin - pharmacokinetics Scientific imaging Studies Tandem Mass Spectrometry - methods Urine Young Adult
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