Clinical picture: bronchiolitis obliterans with organising pneumonia during interferon beta-1a treatment

A 49-year-old man with an 8-year history of multiple sclerosis was prescribed treatment with interferon beta-1a (IFN(beta)-1a) (Avonex, Biogen), 30 mg per week. 3 months later he presented with a progressive, unproductive cough and right hemithoracic pain without fever. Full blood count showed sligh...

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Veröffentlicht in:The Lancet (British edition) 2001-03, Vol.357 (9258), p.751
Hauptverfasser: Ferriby, D, Stojkovic, T
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Stojkovic, T
description A 49-year-old man with an 8-year history of multiple sclerosis was prescribed treatment with interferon beta-1a (IFN(beta)-1a) (Avonex, Biogen), 30 mg per week. 3 months later he presented with a progressive, unproductive cough and right hemithoracic pain without fever. Full blood count showed slight leucocytosis (13x10^sup 9^ cells/L) with 75% neutrophils. The erythrocyte sedimentation rate was raised (50 mm/h).
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subjects Bronchitis
Case studies
Cryptogenic Organizing Pneumonia - chemically induced
Cryptogenic Organizing Pneumonia - diagnostic imaging
Humans
Interferon beta-1a
Interferon-beta - adverse effects
Interferon-beta - therapeutic use
Lung - diagnostic imaging
Male
Middle Aged
Pneumonia
Tomography, X-Ray Computed
title Clinical picture: bronchiolitis obliterans with organising pneumonia during interferon beta-1a treatment
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