Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings

(±)3,4-methylenedioxymethamphetamine (MDMA, “Ecstasy”) is a popular recreational drug that selectively damages brain serotonin (5-HT) neurons in animals at doses that closely approach those used by humans. We investigated the status of brain 5-HT neurons in MDMA users. We enrolled 14 previous users...

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Veröffentlicht in:	The Lancet (British edition) 1998-10, Vol.352 (9138), p.1433-1437
Hauptverfasser:	McCann, UD, Szabo, Z, Scheffel, U, Dannals, RF, Ricaurte, GA
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Brain Brain - drug effects Drug addictions Drugs Emissions Female Humans Male Medical sciences N-Methyl-3,4-methylenedioxyamphetamine - adverse effects Neurons Neurons - drug effects Neurons - metabolism Serotonin - metabolism Serotonin Agents - adverse effects Tomography, Emission-Computed Toxicology
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