Tunnelled pleural catheters in malignant pleural effusion – Author's reply
In fact, the lack of a negative effect of tunnelled pleural catheter treatment on survival has been well documented in a randomised controlled trial in which the technique was compared with doxycycline pleurodesis: survival rates were identical between the two groups.3 I declare that I have no confl...
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| Veröffentlicht in: | The Lancet (British edition) 2007-08, Vol.370 (9585), p.387-387 |
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| creator | Aelony, Yossef |
| description | In fact, the lack of a negative effect of tunnelled pleural catheter treatment on survival has been well documented in a randomised controlled trial in which the technique was compared with doxycycline pleurodesis: survival rates were identical between the two groups.3 I declare that I have no conflict of interest. [...] it has been suggested that, since malignant pleural mesothelioma is pauci vascular, effective pleurodesis could deprive this neoplasm of important pleural fluid nutrients.2 And fourth, talc could function as a specific tumour suppressant.3 Permanent suppression of the effusion and talc tumour suppression could explain why talc poudrage-which is more effective than most pleural sclerosants-might be associated with longer survival in malignant pleural mesothelioma.4 Tremblay's reference 3 shows that a relatively inferior form of pleurodesisdoxycycline instillation-was associated with the same survival as the tunnelled catheter. |
| doi_str_mv | 10.1016/S0140-6736(07)61190-8 |
| format | Article |
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[...] it has been suggested that, since malignant pleural mesothelioma is pauci vascular, effective pleurodesis could deprive this neoplasm of important pleural fluid nutrients.2 And fourth, talc could function as a specific tumour suppressant.3 Permanent suppression of the effusion and talc tumour suppression could explain why talc poudrage-which is more effective than most pleural sclerosants-might be associated with longer survival in malignant pleural mesothelioma.4 Tremblay's reference 3 shows that a relatively inferior form of pleurodesisdoxycycline instillation-was associated with the same survival as the tunnelled catheter.</description><identifier>ISSN: 0140-6736</identifier><identifier>EISSN: 1474-547X</identifier><identifier>DOI: 10.1016/S0140-6736(07)61190-8</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>London: Elsevier Ltd</publisher><subject>Catheters ; Conflicts of interest ; Internal Medicine ; Life expectancy ; Medical instruments ; Medical treatment ; Mesothelioma ; Respiratory distress syndrome ; Survival</subject><ispartof>The Lancet (British edition), 2007-08, Vol.370 (9585), p.387-387</ispartof><rights>Elsevier Ltd</rights><rights>2007 Elsevier Ltd</rights><rights>Copyright Elsevier Limited Aug 4-Aug 10, 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c306t-bcda9b2019bccdaed3c122078c8b31b9951d2e621057dba526b11c06633623813</citedby><cites>FETCH-LOGICAL-c306t-bcda9b2019bccdaed3c122078c8b31b9951d2e621057dba526b11c06633623813</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/198979061?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64389,72469</link.rule.ids></links><search><creatorcontrib>Aelony, Yossef</creatorcontrib><title>Tunnelled pleural catheters in malignant pleural effusion – Author's reply</title><title>The Lancet (British edition)</title><description>In fact, the lack of a negative effect of tunnelled pleural catheter treatment on survival has been well documented in a randomised controlled trial in which the technique was compared with doxycycline pleurodesis: survival rates were identical between the two groups.3 I declare that I have no conflict of interest. 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[...] it has been suggested that, since malignant pleural mesothelioma is pauci vascular, effective pleurodesis could deprive this neoplasm of important pleural fluid nutrients.2 And fourth, talc could function as a specific tumour suppressant.3 Permanent suppression of the effusion and talc tumour suppression could explain why talc poudrage-which is more effective than most pleural sclerosants-might be associated with longer survival in malignant pleural mesothelioma.4 Tremblay's reference 3 shows that a relatively inferior form of pleurodesisdoxycycline instillation-was associated with the same survival as the tunnelled catheter.</abstract><cop>London</cop><pub>Elsevier Ltd</pub><doi>10.1016/S0140-6736(07)61190-8</doi><tpages>1</tpages></addata></record> |
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| source | Elsevier ScienceDirect Journals Complete; ProQuest Central UK/Ireland |
| subjects | Catheters Conflicts of interest Internal Medicine Life expectancy Medical instruments Medical treatment Mesothelioma Respiratory distress syndrome Survival |
| title | Tunnelled pleural catheters in malignant pleural effusion – Author's reply |
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