Pain and remote weakness in limbs injected with botulinum toxin A for writer's cramp

We describe two cases of a syndrome resembling neuralgic amyotrophy that occurred in limbs injected with botulinum toxin for writer's cramp. In both cases, one of the injections was followed by pain and the next, 7-10 weeks later, by weakness. We believe that unexplained pain in the shoulder re...

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Veröffentlicht in:	The Lancet (British edition) 1995-07, Vol.346 (8968), p.154-156
Hauptverfasser:	Sheean, G.L., Murray, N.M.F., Marsden, C.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Botulinum Toxins - administration & dosage Botulinum Toxins - adverse effects Botulinum Toxins - therapeutic use Brachial Plexus Neuritis - etiology Drug toxicity and drugs side effects treatment Female Humans Injection Injections, Intramuscular Medical research Medical sciences Middle Aged Muscle Cramp - therapy Muscular system Neurological disorders Pain Pain - etiology Pharmacology. Drug treatments Shoulder Toxicity: nervous system and muscle Toxins
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Beschreibung
Zusammenfassung:	We describe two cases of a syndrome resembling neuralgic amyotrophy that occurred in limbs injected with botulinum toxin for writer's cramp. In both cases, one of the injections was followed by pain and the next, 7-10 weeks later, by weakness. We believe that unexplained pain in the shoulder region after an injection of botulinum toxin contraindicates a second injection.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/S0140-6736(95)91212-6