PRIMARY BILIARY CIRRHOSIS: IDENTIFICATION OF TWO MAJOR M2 MITOCHONDRIAL AUTOANTIGENS

Primary biliary cirrhosis (PBC) is characterised by the presence of antimitochondrial antibodies. The PBC-specific, immunoreactive, trypsin-sensitive antigens on the inner mitochondrial membrane (M2) have hitherto not been identified. A major 70 kD M2 autoantigen is the E2 component (lipoate acetylt...

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Veröffentlicht in:	The Lancet (British edition) 1988-05, Vol.331 (8594), p.1067-1070
Hauptverfasser:	Yeaman, S.J., Danner, D.J., Mutimer, D.J., Fussey, S.P.M., James, O.F.W., Bassendine, M.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Dehydrogenase Gastroenterology. Liver. Pancreas. Abdomen Liver Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical research Medical sciences Other diseases. Semiology
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