Effective graft‐versus‐leukaemia effect after allogeneic stem cell transplantation using reduced‐intensity preparative regimens in Fanconi anaemia patients with myelodysplastic syndrome or acute myeloid leukaemia

Allogeneic transplantation is the only curative treatment for Fanconi anaemia (FA) patients who develop myeloid malignancies. Dose‐intensive preparative regimens, to decrease disease recurrence, lead to unacceptable transplant‐related toxicity in FA. We report the outcome of three FA patients with s...

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Veröffentlicht in:	British journal of haematology 2003-09, Vol.122 (5), p.806-809
Hauptverfasser:	Guardiola, Philippe, Kurre, Peter, Vlad, Amalia, Cayuela, Jean‐Michel, Espérou, Hélène, Devergie, Agnès, Ribaud, Patricia, Socié, Gérard, Richard, Patrice, Traineau, Richard, Storb, Rainer, Gluckman, Eliane
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute leukaemia Adult allogeneic stem cell trans‐plantation Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow, stem cells transplantation. Graft versus host reaction Child Fanconi anaemia Fanconi Anemia - surgery Fatal Outcome Female Graft vs Leukemia Effect graft‐versus‐leukaemia effect Hematologic and hematopoietic diseases Hematology Humans Leukemia, Myeloid - surgery Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences myelodysplasia Myelodysplastic Syndromes - surgery Reoperation Stem Cell Transplantation Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Conditioning - methods Transplantation, Homologous
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