Allogeneic stem cell transplantation for severe acquired aplastic anaemia using a fludarabine‐based preparative regimen

Summary We reviewed our experience in the treatment of 13 patients with severe acquired aplastic anaemia, using a newly developed non‐myeloablative regimen consisting of fludarabine (total dose 180 mg/m2), cyclophosphamide (total dose 120 mg/kg), and antithymocyte globulin (total dose 40 mg/kg). All...

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Veröffentlicht in:	British journal of haematology 2006-06, Vol.133 (6), p.649-654
Hauptverfasser:	Resnick, Igor B., Aker, Memet, Shapira, Michael Y., Tsirigotis, Panagiotis D., Bitan, Menachem, Abdul‐Hai, Ali, Samuel, Simcha, Ackerstein, Aliza, Gesundheit, Benjamin, Zilberman, Irina, Miron, Svetlana, Yoffe, Luba, Lvovich, Alex, Slavin, Shimon, Or, Reuven
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anemia, Aplastic - therapy Antilymphocyte Serum - therapeutic use Biological and medical sciences Child Cyclophosphamide - therapeutic use Female fludarabine Graft vs Host Disease - prevention & control Hematologic and hematopoietic diseases Hematology Hematopoietic Stem Cell Transplantation - methods Humans Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged Mucositis - chemically induced non‐myeloablative HSCT Opportunistic Infections - etiology Pilot Projects Quality of Life severe aplastic anaemia Transplantation Chimera Transplantation Conditioning - methods Treatment Outcome Vidarabine - analogs & derivatives Vidarabine - therapeutic use
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