$Overcoming drug resistance in hormone- and drug-refractory prostate cancer cell line, PC-3 by docetaxel and gossypol combination$

Overcoming drug resistance in hormone- and drug-refractory prostate cancer cell line, PC-3 by docetaxel and gossypol combination

Drug resistance is a significant challenge of daily oncology practice. Docetaxel and gossypol both have antitumoral activity in hormone-refractory prostate cancer (HRPC). Our results revealed that docetaxel and gossypol were synergistically cytotoxic and apoptotic in PC-3 cells in a dose- and time-d...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular biology reports 2010-03, Vol.37 (3), p.1269-1277
Hauptverfasser:	Cengiz, Ercument, Karaca, Burcak, Kucukzeybek, Yuksel, Gorumlu, Gurbuz, Gul, Mustafa K., Erten, Cigdem, Atmaca, Harika, Uzunoglu, Selim, Karabulut, Bulent, Sanli, Ulus A., Uslu, Ruchan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Apoptosis - drug effects Biomedical and Life Sciences Cell Line, Tumor Chemotherapy DNA, Complementary - genetics Dose-Response Relationship, Drug Drug resistance Drug Resistance, Neoplasm - physiology Drug Therapy, Combination Enzyme-Linked Immunosorbent Assay Gene Expression Profiling Gene Expression Regulation, Neoplastic - drug effects Gossypol - pharmacology Histology Hormones Humans Life Sciences Male Morphology Oncology Pharmacology Prostate cancer Prostatic Neoplasms - drug therapy Taxoids - pharmacology Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!