Cyclosporine for Plaque-Type Psoriasis: Results of a Multidose, Double-Blind Trial

The effectiveness of cyclosporine in the treatment of psoriasis was a serendipitous finding by Mueller and Herrmann, 1 who included four patients with psoriatic arthritis and psoriasis in a study of therapy for rheumatoid arthritis. We confirmed this finding in a double-blind trial of the efficacy o...

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Veröffentlicht in:	The New England journal of medicine 1991-01, Vol.324 (5), p.277-284
Hauptverfasser:	Ellis, Charles N, Fradin, Mark S, Messana, Joseph M, Brown, Marc D, Siegel, Michael T, Hartley, A. Howland, Rocher, Leslie L, Wheeler, Suzanne, Hamilton, Ted A, Parish, Thomas G, Ellis-Madu, Mary, Duell, Elizabeth, Annesley, Thomas M, Cooper, Kevin D, Voorhees, John J
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Aged Antigens Arthritis Bilirubin Biological and medical sciences Blood pressure Body weight Cholesterol Creatinine Cyclosporins Cyclosporins - administration & dosage Cyclosporins - adverse effects Cyclosporins - therapeutic use Dermatology Double-Blind Method Drug dosages Female Glomerular filtration rate Humans Hypersensitivity, Delayed - immunology Immunomodulators Kidney - drug effects Laboratories Male Medical sciences Middle Aged Oral administration Pharmacology. Drug treatments Psoriasis Psoriasis - drug therapy Serum levels Side effects Skin - immunology Skin tests Uric acid
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