Ameliorative Effect of VE, IGF-I, and hCG on the Fluoride-Induced Testosterone Release Suppression in Mice Leydig Cells

Excessive consumption of fluoride (F) through drinking, eating, and/or environmental contaminants induces chronic toxicity known as fluorosis. Our previous research has shown that fluorosis was associated with male reproductive disorders. The current study is designed to explain the protective effec...

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Veröffentlicht in:	Biological trace element research 2018, Vol.181 (1), p.95-103
Hauptverfasser:	Yu, Yuxiang, Han, Yongli, Niu, Ruiyan, Wang, Jundong, Manthari, Ram Kumar, Ommati, Mohammad Mehdi, Sun, Zilong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biomedical and Life Sciences Biotechnology Cell growth Cell proliferation Chorionic gonadotropin Chorionic Gonadotropin - metabolism Chronic toxicity Contaminants Fluorides Fluorides - antagonists & inhibitors Fluorides - pharmacology Fluorosis Gene expression Gonadotropins Growth factors Insulin Insulin-like growth factor I Insulin-Like Growth Factor I - metabolism Insulin-like growth factors Leydig cells Leydig Cells - drug effects Leydig Cells - metabolism Life Sciences Male Mice Mice, Inbred Strains Nutrition Oncology Pituitary (anterior) Proliferation Reproductive disorders Rodents Secretion Steroidogenesis Testosterone Testosterone - antagonists & inhibitors Testosterone - metabolism Tocopherol Toxicity Vitamin E Vitamin E - metabolism Vitamins
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