Pharmacokinetics of rectal tramadol in postoperative paediatric patients

Postoperative analgesia in children may be improved by using tramadol. The pharmacokinetics of rectal tramadol in young children were therefore investigated. The pharmacokinetics of rectal tramadol and its active metabolite were studied in 12 young children (age: 1–6 yr) postoperatively. On the basi...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2004-08, Vol.93 (2), p.224-227
Hauptverfasser:	Zwaveling, J., Bubbers, S., van Meurs, A.H.J., Schoemaker, R.C., van Heel, I. Ruijs-Dudok, Vermeij, P., Burggraaf, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Rectal analgesia analgesia, paediatric analgesic administration analgesic administration, rectal analgesics opioid analgesics opioid, tramadol Analgesics, Opioid - administration & dosage Analgesics, Opioid - blood Analgesics, Opioid - pharmacokinetics Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Child Child, Preschool Female Half-Life Humans Infant Male Medical sciences Models, Biological paediatric pain Pain, Postoperative - blood Pain, Postoperative - prevention & control rectal Suppositories tramadol Tramadol - administration & dosage Tramadol - blood Tramadol - pharmacokinetics
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