Local anaesthetic sensitivities of cloned HERG channels from human heart: comparison with HERG/MiRP1 and HERG/MiRP1^sub T8A

BACKGROUND: Myocardial potassium channels are complexes formed by different subunits. The subunit composition may influence the cardiotoxic action of local anaesthetics. The effects of amide local anaesthetics on HERG channels co-expressed with the putative subunit MiRP1 have not been established. I...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2004-01, Vol.92 (1), p.93
Hauptverfasser:	Friederich, P, Solth, A, Schillemeit, S, Isbrandt, D
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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