Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia

Perioperative use of dexmedetomidine is associated with reduction in postoperative analgesic requirements. This study examined whether dexmedetomidine added to i.v. patient-controlled analgesia (PCA) morphine could improve analgesia while reducing opioid-related side-effects. In this double-blinded,...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2009-01, Vol.102 (1), p.117-122
Hauptverfasser:	Lin, T.-F., Yeh, Y.-C., Lin, F.-S., Wang, Y.-P., Lin, C.-J., Sun, W.-Z., Fan, S.-Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult analgesia analgesia, patient-controlled Analgesia, Patient-Controlled - methods analgesia, postoperative analgesics opioid analgesics opioid, morphine Analgesics, Non-Narcotic - administration & dosage Analgesics, Non-Narcotic - adverse effects Analgesics, Opioid - administration & dosage Analgesics, Opioid - adverse effects Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Pressure - drug effects dexmedetomidine Dexmedetomidine - administration & dosage Dexmedetomidine - adverse effects Double-Blind Method Drug Administration Schedule Drug Combinations Female Heart Rate - drug effects Humans Hysterectomy Infusions, Intravenous Medical sciences Middle Aged morphine Morphine - administration & dosage Morphine - adverse effects Pain, Postoperative - prevention & control patient-controlled pharmacology pharmacology, dexmedetomidine postoperative Postoperative Nausea and Vomiting - chemically induced
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