Comparison of the effects of intrathecal administration of levobupivacaine and lidocaine on the prostaglandin E^sub 2^ and glutamate increases in cerebrospinal fluid: a microdialysis study in freely moving rats

BACKGROUND: Bupivacaine has a lower incidence of transient neurological symptoms than lidocaine after intrathecal (i.t.) injection. The increased toxic potential of lidocaine does not support its use in the clinical setting and could be related to augmented levels of spinal prostaglandin E(2) (PGE(2...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2009-04, Vol.102 (4), p.540
Hauptverfasser:	Umbrain, V J, Lauwers, M-H, Shi, L, Smolders, I, Michotte, Y, Poelaert, J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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