Effect of intravenous vasopressor on spread of spinal anaesthesia and fetal acid–base equilibrium

We previously found rostral spread of spinal plain levobupivacaine to be less with prophylactic i.v. phenylephrine than with ephedrine during Caesarean delivery. This study investigated whether rostral spread of spinal hyperbaric bupivacaine is also less with phenylephrine than with ephedrine. The s...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2007-05, Vol.98 (5), p.649-656
Hauptverfasser:	Cooper, D.W., Gibb, S.C., Meek, T., Owen, S., Kokri, M.S., Malik, A.T., Koneti, K.K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid-Base Equilibrium - drug effects Acidosis - chemically induced acid–base equilibrium acid–base equilibrium, pH Adult anaesthetic techniques anaesthetic techniques, subarachnoid Anesthesia Anesthesia, Obstetrical - methods Anesthesia, Spinal - methods Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Local - pharmacokinetics Biological and medical sciences Bupivacaine - pharmacokinetics Cesarean Section Double-Blind Method Drug Interactions ephedrine Ephedrine - adverse effects Ephedrine - pharmacology Female fetus Fetus - metabolism Humans Maternal-Fetal Exchange Medical sciences phenylephrine Phenylephrine - pharmacology Pregnancy subarachnoid sympathetic nervous system sympathetic nervous system, ephedrine sympathetic nervous system, phenylephrine Vasoconstrictor Agents - adverse effects Vasoconstrictor Agents - pharmacology
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