Negative modulation of the GABAA[rho]1 receptor function by l-cysteine

l-Cysteine is an endogenous sulfur-containing amino acid with multiple and varied roles in the central nervous system, including neuroprotection and the maintenance of the redox balance. However, it was also suggested as an excitotoxic agent implicated in the pathogenesis of neurological disorders s...

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Veröffentlicht in:	Journal of neurochemistry 2018-01, Vol.144 (1), p.50
Hauptverfasser:	Beltran Gonzalez, Andrea N, Vicentini, Florencia, Calvo, Daniel J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylation Alzheimer's disease Amino acids Calcium Calcium channels Calcium channels (voltage-gated) Central nervous system Channels Chloride currents Chlorides Cysteine Excitotoxicity Glutamatergic transmission Glutamic acid receptors (ionotropic) Inhibition Modulation Movement disorders N-Methyl-D-aspartic acid receptors Neurodegenerative diseases Neurological diseases Neuroprotection Neurotransmission Oocytes Parkinson's disease Pathogenesis Receptors Retina Sulfhydryl groups Sulfur γ-Aminobutyric acid A receptors
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