Phenotyping malignant hyperthermia susceptability by measuring halothane-induced changes in myoplasmic calcium concentration in cultured human skeletal muscle cells

BACKGROUND: Malignant hyperthermia (MH) is a potentially lethal disease triggered by volatile anaesthetics and succinylcholine in genetically predisposed individuals. Because of the heterogenetic nature of MH, a simple genetic-based diagnostic test is not feasible and diagnosis requires an invasive...

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Veröffentlicht in:British journal of anaesthesia : BJA 2002-10, Vol.89 (4), p.571
Hauptverfasser: Girard, T, Treves, S, Censier, K, Mueller, C R
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Sprache:eng
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