Docking, characterization and investigation of ß-cyclodextrin complexed with farnesol, an acyclic sesquiterpene alcohol, produces orofacial antinociceptive profile in experimental protocols

In this study, an inclusion complex with β-cyclodextrin and farnesol (βCD/FAR) was used to improve the physico-chemical and pharmacological properties of farnesol. The samples were obtained using the physical mixture, paste and slurry complexation methods and characterized by variety of methods. To...

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Veröffentlicht in:	Process biochemistry (1991) 2017-11, Vol.62, p.193
Hauptverfasser:	Silva, Juliane Cabral, Alcantara, Lidianne Fábia de Moraes, Soares, Juliana Mikaelly Dias, e Silva, Mariana Gama, de Lavor, Érica Martins, Andrade, Valléria Matos, Menezes, Paula dos Passos, Araújo, Adriano Antunes de Souza, Leite, Laura Hévila Inocêncio, de Menezes, Irwin Rose Alencar, Scotti, Luciana, Scotti, Marcus T, Oliveira, Rita CM, Quintans, Jullyana SS, Almeida, Jackson Roberto Guedes Silva, Quintans-Júnior, Lucindo José
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols Animal models Capsaicin Channels Complexation Crystals Deformation Deformation mechanisms Docking Energy of formation Farnesol Formaldehyde Glibenclamide Motor task performance Natural products Pain Pain perception Pharmacology Potassium channels Receptors Rubbing Serotonin Serotonin S3 receptors Slurries β-Cyclodextrin
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