Diastereodivergent Henry Reaction for the Stereoselective Construction of Nitrogen‐Containing Tetrasubstituted Carbons: Application to Total Synthesis of Manzacidins A and C

β,β‐Disubstituted β‐amino alcohols has been synthesized in a diastereodivergent manner from chiral secondary nitroalkanes as starting materials. In this key Henry reaction, the use of different protecting groups resulted in the diastereoselective construction of the tetrasubstituted carbon stereocen...

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Veröffentlicht in:	Asian journal of organic chemistry 2017-12, Vol.6 (12), p.1760-1763
Hauptverfasser:	Kudoh, Takayuki, Araki, Yuya, Miyoshi, Natsumi, Tanioka, Mizuho, Sakakura, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols diastereodivergent Henry reaction manzacidin Organic chemistry Synthesis tetrasubstituted carbon β,β-disubstituted β-amino alcohol
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