Vitamin D Deficiency in Early Infancy1
We analyzed the characteristics of young infants diagnosed with vitamin D deficiency in early infancy at 2 medical centers in Turkey. In this retrospective, cross-sectional study, the clinical, biochemical, and radiographic findings of infants who were diagnosed with vitamin D deficiency at
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| Veröffentlicht in: | The Journal of nutrition 2005-02, Vol.135 (2), p.279-282 |
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| container_title | The Journal of nutrition |
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| creator | Hatun, Sukru Ozkan, Behzat Orbak, Zerrin Doneray, Hakan Cizmecioglu, Filiz Toprak, Demet Calikoglu, Ali Süha |
| description | We analyzed the characteristics of young infants diagnosed with vitamin D deficiency in early infancy at 2 medical centers in Turkey. In this retrospective, cross-sectional study, the clinical, biochemical, and radiographic findings of infants who were diagnosed with vitamin D deficiency at |
| doi_str_mv | 10.1093/jn/135.2.279 |
| format | Article |
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In this retrospective, cross-sectional study, the clinical, biochemical, and radiographic findings of infants who were diagnosed with vitamin D deficiency at <3 mo of age between May 2001 and May 2003 were reviewed. A total of 42 infants (27 boys and 15 girls) were diagnosed with vitamin D deficiency in the first 3 mo of life during this 2-y period. The age of infants at diagnosis was 60 ± 19 d (range 32–112 d). The majority (78.7%) presented with seizures. No skeletal deformities were detected clinically, and radiological findings were subtle. All infants had low serum calcium levels but serum phosphorous levels varied. Eight infants (19.0%) had low, 19 (45.3%) had normal, and 15 (35.7%) had elevated serum phosphorous levels. Serum 25-hydroxyvitamin D levels in those measured (29 infants and 15 mothers) were <37.5 nmol/L. Most infants (83%) were exclusively breast-fed without supplemental vitamin D, and none of the mothers were supplemented with vitamin D during pregnancy. All mothers had limited sunlight exposure and 33 of 42 mothers (78.6%) wore concealing clothing. The majority of young infants diagnosed with vitamin D deficiency present with seizures, have low dietary vitamin D intake, and mothers with poor vitamin D reserves. Evaluation of vitamin D status should be included into the workup of hypocalcemia in early infancy. Prevention of deficiency by supplementing pregnant women and infants who are exclusively breast-fed is essential.</description><identifier>ISSN: 0022-3166</identifier><identifier>EISSN: 1541-6100</identifier><identifier>DOI: 10.1093/jn/135.2.279</identifier><identifier>CODEN: JONUAI</identifier><language>eng</language><publisher>Bethesda: Elsevier Inc</publisher><subject>Babies ; Calcium ; Dietary supplements ; hypocalcemia ; Nutrition ; Vitamin D ; vitamin D deficiency</subject><ispartof>The Journal of nutrition, 2005-02, Vol.135 (2), p.279-282</ispartof><rights>2005 American Society for Nutrition.</rights><rights>Copyright American Institute of Nutrition Feb 2005</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids></links><search><creatorcontrib>Hatun, Sukru</creatorcontrib><creatorcontrib>Ozkan, Behzat</creatorcontrib><creatorcontrib>Orbak, Zerrin</creatorcontrib><creatorcontrib>Doneray, Hakan</creatorcontrib><creatorcontrib>Cizmecioglu, Filiz</creatorcontrib><creatorcontrib>Toprak, Demet</creatorcontrib><creatorcontrib>Calikoglu, Ali Süha</creatorcontrib><title>Vitamin D Deficiency in Early Infancy1</title><title>The Journal of nutrition</title><description>We analyzed the characteristics of young infants diagnosed with vitamin D deficiency in early infancy at 2 medical centers in Turkey. In this retrospective, cross-sectional study, the clinical, biochemical, and radiographic findings of infants who were diagnosed with vitamin D deficiency at <3 mo of age between May 2001 and May 2003 were reviewed. A total of 42 infants (27 boys and 15 girls) were diagnosed with vitamin D deficiency in the first 3 mo of life during this 2-y period. The age of infants at diagnosis was 60 ± 19 d (range 32–112 d). The majority (78.7%) presented with seizures. No skeletal deformities were detected clinically, and radiological findings were subtle. All infants had low serum calcium levels but serum phosphorous levels varied. Eight infants (19.0%) had low, 19 (45.3%) had normal, and 15 (35.7%) had elevated serum phosphorous levels. Serum 25-hydroxyvitamin D levels in those measured (29 infants and 15 mothers) were <37.5 nmol/L. Most infants (83%) were exclusively breast-fed without supplemental vitamin D, and none of the mothers were supplemented with vitamin D during pregnancy. All mothers had limited sunlight exposure and 33 of 42 mothers (78.6%) wore concealing clothing. The majority of young infants diagnosed with vitamin D deficiency present with seizures, have low dietary vitamin D intake, and mothers with poor vitamin D reserves. Evaluation of vitamin D status should be included into the workup of hypocalcemia in early infancy. Prevention of deficiency by supplementing pregnant women and infants who are exclusively breast-fed is essential.</description><subject>Babies</subject><subject>Calcium</subject><subject>Dietary supplements</subject><subject>hypocalcemia</subject><subject>Nutrition</subject><subject>Vitamin D</subject><subject>vitamin D deficiency</subject><issn>0022-3166</issn><issn>1541-6100</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNotkE1Lw0AQhhdRMFZv_oDgwVvS2c9kj9JWLRS8FK_LZncWNtSNJqnQf-9qPQ0zPLzz8hByT6GmoPmyT0vKZc1q1ugLUlApaKUowCUpABirOFXqmtxMUw8AVOi2II_vcbYfMZXrco0huojJncq8b-x4OJXbFGw-0FtyFexhwrv_uSD7581-9Vrt3l62q6ddhY3glRfKNuh8a5GF4GwnBKDnTinptbNBBUY5Q58J5WVovbdWMd51DGUrOfAFeTjHfo7D1xGn2fTDcUz5o6G6EQ1o4BlSZwhzke-Io5n-aqOPI7rZ-CEaCubXiOmTyUYMM9kI_wG_jlNK</recordid><startdate>200502</startdate><enddate>200502</enddate><creator>Hatun, Sukru</creator><creator>Ozkan, Behzat</creator><creator>Orbak, Zerrin</creator><creator>Doneray, Hakan</creator><creator>Cizmecioglu, Filiz</creator><creator>Toprak, Demet</creator><creator>Calikoglu, Ali Süha</creator><general>Elsevier Inc</general><general>American Institute of Nutrition</general><scope>6I.</scope><scope>AAFTH</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>200502</creationdate><title>Vitamin D Deficiency in Early Infancy1</title><author>Hatun, Sukru ; Ozkan, Behzat ; Orbak, Zerrin ; Doneray, Hakan ; Cizmecioglu, Filiz ; Toprak, Demet ; Calikoglu, Ali Süha</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e743-d46a7ecd8ae2ffcab440ed3c665d9caf6f2132edcd86d5f8ddaa623bb2e585303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Babies</topic><topic>Calcium</topic><topic>Dietary supplements</topic><topic>hypocalcemia</topic><topic>Nutrition</topic><topic>Vitamin D</topic><topic>vitamin D deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hatun, Sukru</creatorcontrib><creatorcontrib>Ozkan, Behzat</creatorcontrib><creatorcontrib>Orbak, Zerrin</creatorcontrib><creatorcontrib>Doneray, Hakan</creatorcontrib><creatorcontrib>Cizmecioglu, Filiz</creatorcontrib><creatorcontrib>Toprak, Demet</creatorcontrib><creatorcontrib>Calikoglu, Ali Süha</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>The Journal of nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hatun, Sukru</au><au>Ozkan, Behzat</au><au>Orbak, Zerrin</au><au>Doneray, Hakan</au><au>Cizmecioglu, Filiz</au><au>Toprak, Demet</au><au>Calikoglu, Ali Süha</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin D Deficiency in Early Infancy1</atitle><jtitle>The Journal of nutrition</jtitle><date>2005-02</date><risdate>2005</risdate><volume>135</volume><issue>2</issue><spage>279</spage><epage>282</epage><pages>279-282</pages><issn>0022-3166</issn><eissn>1541-6100</eissn><coden>JONUAI</coden><abstract>We analyzed the characteristics of young infants diagnosed with vitamin D deficiency in early infancy at 2 medical centers in Turkey. In this retrospective, cross-sectional study, the clinical, biochemical, and radiographic findings of infants who were diagnosed with vitamin D deficiency at <3 mo of age between May 2001 and May 2003 were reviewed. A total of 42 infants (27 boys and 15 girls) were diagnosed with vitamin D deficiency in the first 3 mo of life during this 2-y period. The age of infants at diagnosis was 60 ± 19 d (range 32–112 d). The majority (78.7%) presented with seizures. No skeletal deformities were detected clinically, and radiological findings were subtle. All infants had low serum calcium levels but serum phosphorous levels varied. Eight infants (19.0%) had low, 19 (45.3%) had normal, and 15 (35.7%) had elevated serum phosphorous levels. Serum 25-hydroxyvitamin D levels in those measured (29 infants and 15 mothers) were <37.5 nmol/L. Most infants (83%) were exclusively breast-fed without supplemental vitamin D, and none of the mothers were supplemented with vitamin D during pregnancy. All mothers had limited sunlight exposure and 33 of 42 mothers (78.6%) wore concealing clothing. The majority of young infants diagnosed with vitamin D deficiency present with seizures, have low dietary vitamin D intake, and mothers with poor vitamin D reserves. Evaluation of vitamin D status should be included into the workup of hypocalcemia in early infancy. Prevention of deficiency by supplementing pregnant women and infants who are exclusively breast-fed is essential.</abstract><cop>Bethesda</cop><pub>Elsevier Inc</pub><doi>10.1093/jn/135.2.279</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | The Journal of nutrition, 2005-02, Vol.135 (2), p.279-282 |
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| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Babies Calcium Dietary supplements hypocalcemia Nutrition Vitamin D vitamin D deficiency |
| title | Vitamin D Deficiency in Early Infancy1 |
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