Biomarkers of Human Colonic Cell Growth Are Influenced Differently by a History of Colonic Neoplasia and the Consumption of Acarbose

The nutritional effects of butyrate on the colonic mucosa and studies of transformed cells suggest that butyrate has anti-colon cancer effects. If butyrate has antineoplastic effects, mucosal growth contrasts between normal subjects and those with a history of colonic neoplasia would parallel change...

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Veröffentlicht in:	The Journal of nutrition 2000-11, Vol.130 (11), p.2718-2725
Hauptverfasser:	Weaver, Gary A., Tangel, Colette T., Krause, Jean A., Parfitt, Margaret M., Stragand, James J., Jenkins, Paul L., Erb, Tara A., Davidson, Roger H., Alpern, Harlan D., Guiney, William B., Higgins, Paul J.
Format:	Artikel
Sprache:	eng
Schlagworte:	acarbose Acarbose - therapeutic use Adult Aged Antimetabolites - pharmacokinetics Biological and medical sciences Biomarkers Bromodeoxyuridine - pharmacokinetics butyric acid Carcinogenesis, carcinogens and anticarcinogens Carcinoma - pathology Carcinoma - prevention & control Case-Control Studies Cell Division - drug effects Cells colonic crypt cell proliferation Colonic Neoplasms - pathology Colonic Neoplasms - prevention & control Colonoscopy Colorectal cancer Cross-Over Studies Diet Enzyme Inhibitors - therapeutic use Fatty acids Fatty Acids, Volatile - metabolism Female Foods and miscellaneous Gastroenterology. Liver. Pancreas. Abdomen human colon cancer Humans Intestinal Mucosa - drug effects Intestinal Mucosa - metabolism Ki-67 Antigen - isolation & purification Male Medical sciences Middle Aged Nutrition short-chain fatty acids Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
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