Soybeans isoflavones, genistein and genistin, inhibit rat myoblast proliferation, fusion and myotube protein synthesis

The isoflavones, genistein and genistin, are cytotoxic in vitro (e.g. , inhibition of cell proliferation), due in part to inhibition of protein tyrosine kinase and DNA topoisomerase activities. Normal cell functions associated with these enzymatic activities could potentially be impaired in animals...

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Veröffentlicht in:The Journal of nutrition 1999-07, Vol.129 (7), p.1291
Hauptverfasser: Ji, Shaoquan, Willis, Gawain M, Frank, G Robert, Cornelius, Steven G, Spurlock, Michael E
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Sprache:eng
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