[gamma]-Glutamyl Hydrolase, Not Glutamate Carboxypeptidase II, Hydrolyzes Dietary Folate in Rat Small Intestine1,2

Dietary polyglutamyl folates are hydrolyzed to monoglutamyl folate derivatives prior to intestinal transport. In humans and pigs, the reaction occurs at pH 6.5 at the jejunal brush border membrane by folate hydrolase and is encoded by the glutamate carboxypeptidase II (GCPII) gene. Intracellular fol...

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Veröffentlicht in:	The Journal of nutrition 2007-05, Vol.137 (5), p.1149
Hauptverfasser:	Shafizadeh, Tracy B, Halsted, Charles H
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile Enzymes Rodents Small intestine Vitamin B
Online-Zugang:	Volltext
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