Organocatalytic Asymmetric Tandem α‐Aminooxylation–Henry Reactions for the Synthesis of 1,2‐Diols: Total Synthesis of (–)‐l‐threo‐Sphinganine

A new and rapid asymmetric synthesis of anti‐ and syn‐β,γ‐dihydroxynitroalkanes through an organocatalytic tandem α‐aminooxylation–Henry reaction is described. The target diol derivatives were synthesized in good yields, with excellent enantioselectivities, and low to moderate diasteroselectivities,...

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Veröffentlicht in:	European journal of organic chemistry 2017-12, Vol.2017 (45), p.6700-6707
Hauptverfasser:	Garg, Yuvraj, Kaur, Ramandeep, Kumar Pandey, Satyendra
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymmetric synthesis Cascade chemical reactions Chemical synthesis Copper Diols Henry reaction Organocatalysis Tandem reactions Total synthesis
Online-Zugang:	Volltext
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