Impact of Muscarinic M^sub 3^ Receptor Antagonism on the Risk of Type 2 Diabetes in Antidepressant-Treated Patients: A Case-Controlled Study

M3 muscarinic receptor antagonism has been associated with glucose intolerance and disturbance of insulin secretion. Our objective was to examine the risk of type 2 diabetes mellitus (T2DM) in patients using antidepressants with and without M3 muscarinic receptor antagonism (AD_antaM3 and AD_nonanta...

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Veröffentlicht in:	CNS drugs 2017-06, Vol.31 (6), p.483-493
Hauptverfasser:	Tran, Yen-Hao, Schuiling-Veninga, Catharina C M, Bergman, Jorieke E H, Groen, Henk, Wilffert, Bob
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors (muscarinic) Antidepressants Diabetes Diabetes mellitus Glucose Glucose tolerance Insulin Insulin resistance Insulin secretion Intolerance Morbidity Patients Pharmacy Population Prescription drugs Psychotropic drugs Secretion
Online-Zugang:	Volltext
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