sup 18^F-Tetrafluoroborate, a PET Probe for Imaging Sodium/Iodide Symporter Expression: Whole-Body Biodistribution, Safety, and Radiation Dosimetry in Thyroid Cancer Patients

We report the safety, biodistribution, and internal radiation dosimetry, in humans with thyroid cancer, of 18F-tetrafluoroborate (18F-TFB), a novel PET radioligand for imaging the human sodium/iodide symporter (hNIS). Methods: Serial whole-body PET scans of 5 subjects with recently diagnosed thyroid...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 2017-10, Vol.58 (10), p.1666
Hauptverfasser:	O'Doherty, Jim, Jauregui-Osoro, Maite, Brothwood, Teresa, Szyszko, Teresa, Marsden, Paul K, O'Doherty, Michael J, Cook, Gary JR, Blower, Philip J, Lewington, Val
Format:	Artikel
Sprache:	eng
Schlagworte:	Bladder Cancer Clinical trials Dosimeters Dosimetry Excretion Glands Image analysis Image processing Iodides Kidneys Oncology Organs Pharmaceuticals Pharmacology Positron emission Radiation Radiation dosimetry Radiation effects Radiochemical analysis Radioisotopes Renal function Safety Salivary glands Sodium Sodium iodide symporter Stomach Surgery Thyroid Thyroid cancer Tissues Tomography Urinary bladder Urine
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