Concentration of nitrite and nonthiol nitroso compounds in tissues as a high sensitive marker of leukocyte activity
This paper shows that the inflammation-induced appearance of nitrite and nonthiol nitroso compounds in the hen blood and cow milk is due to oxidation of dinitrosyl iron complexes (DNIC) and nitrosothiols (RSNO) by reactive oxygen species (ROS), which are produced by activated leukocytes. Since DNIC...
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| Veröffentlicht in: | Russian agricultural sciences 2017-09, Vol.43 (5), p.423-426 |
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| container_title | Russian agricultural sciences |
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| creator | Titov, V. Yu Vertiprakhov, V. G. Kosenko, O. V. Fisinin, V. I. Dmitrieva, M. E. Novikova, O. B. Petrov, V. A. |
| description | This paper shows that the inflammation-induced appearance of nitrite and nonthiol nitroso compounds in the hen blood and cow milk is due to oxidation of dinitrosyl iron complexes (DNIC) and nitrosothiols (RSNO) by reactive oxygen species (ROS), which are produced by activated leukocytes. Since DNIC and RSNO are highly effective ROS scavengers, the content of nitrite and nonthiol nitroso compounds can be regarded as one of the most sensitive indicators of leukocyte activation. |
| doi_str_mv | 10.3103/S1068367417050196 |
| format | Article |
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| subjects | Agriculture Animal Husbandry Biomedical and Life Sciences Cell activation Coordination compounds Cow's milk E coli Enzymes Hemoglobin Inflammation Leukocytes Life Sciences Ligands Milk Nitrites Nitroso compounds Oxidation Physiology Plant Biochemistry Reactive oxygen species Salmonella Sensors |
| title | Concentration of nitrite and nonthiol nitroso compounds in tissues as a high sensitive marker of leukocyte activity |
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