A TNF-p100 pathway subverts noncanonical NF-[kappa]B signaling in inflamed secondary lymphoid organs

Lymphotoxin-beta receptor (LT[beta]R) present on stromal cells engages the noncanonical NF-[kappa]B pathway to mediate RelB-dependent expressions of homeostatic chemokines, which direct steady-state ingress of naïve lymphocytes to secondary lymphoid organs (SLOs). In this pathway, NIK promotes parti...

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Veröffentlicht in:	The EMBO journal 2017-12, Vol.36 (23), p.3501
Hauptverfasser:	Mukherjee, Tapas, Chatterjee, Budhaditya, Dhar, Atika, Bais, Sachendra S, Chawla, Meenakshi, Roy, Payel, George, Anna, Bal, Vineeta, Rath, Satyajit, Basak, Soumen
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemokines Homeostasis Immune response Immunization Inflammation Lymphocytes Lymphotoxin Mice Microorganisms NF-κB protein Nuclear transport Organs Proteolysis RelB protein Rodents Signal transduction Signaling Stromal cells T cell receptors Translocation Tumor necrosis factor
Online-Zugang:	Volltext
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