Overexpression of insulin receptor substrate-4 is correlated with clinical staging in colorectal cancer patients

Insulin receptor substrate-4 (IRS-4), a poorly studied member of the IRS family, may play an important role in colorectal cancer (CRC) tumourigenesis. The aim of this pilot study was to elucidate the potential role of IRS-4 in colorectal carcinogenesis by evaluating IRS-4 expression in different typ...

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Veröffentlicht in:	Journal of molecular histology 2018-02, Vol.49 (1), p.39-49
Hauptverfasser:	Sanmartín-Salinas, Patricia, Toledo-Lobo, M. Val, Noguerales-Fraguas, Fernando, Fernández-Contreras, María-Encarnación, Guijarro, Luis G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomedical and Life Sciences Biomedicine Carcinogenesis Cell Biology Cell Nucleus - chemistry Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Developmental Biology Epithelium Female Humans Immunohistochemistry Insulin Insulin Receptor Substrate Proteins - analysis Intestinal Mucosa Life Sciences Localization Male Metastases Middle Aged Mucosa Neoplasm Staging - methods Original Paper Pilot Projects Surgery Tumorigenesis Tumors
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