Allergenicity and cross‐reactivity of Russian olive pollen (Eleagnus angustifolia)
Background: The purposes of this study were: to determine the prevalence of sensitization and immunochemical characterization of Eleagnus angustifolia pollen (Russian olive) that belongs to the family Eleagnaceae. Methods: A total of 134 patients with rhinoconjunctivitis and/or asthma were studied...
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| Veröffentlicht in: | Allergy (Copenhagen) 2004-11, Vol.59 (11), p.1181-1186 |
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| container_title | Allergy (Copenhagen) |
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| creator | Sastre, J. Lluch‐Bernal, M. Bustillo, A. M. G. Carnés, J. Marañón, F. Casanovas, M. Fernández‐Caldas, E. |
| description | Background: The purposes of this study were: to determine the prevalence of sensitization and immunochemical characterization of Eleagnus angustifolia pollen (Russian olive) that belongs to the family Eleagnaceae.
Methods: A total of 134 patients with rhinoconjunctivitis and/or asthma were studied. Its allergenicity, cross‐reactivity with olive pollen and the presence of Ole e 1 and Ole e 4‐like molecules were evaluated.
Results: Eleagnus angustifolia pollen was detected from May to June. Seventy‐three of 134 (30.5%) had positive skin test to E. angustifolia, all of them were positive to olive. There was a good correlation between specific immunoglobulin (Ig)E levels to E. angustifolia and Olea europaea (r = 0.77, P = 0.002). Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS‐PAGE) immunoblots revealed major IgE‐binding bands in the E. angustifolia extract of 43 and 63.7 kDa. The E. angustifolia extract was not able to inhibit olive, whereas O. europaea inhibited E. angustifolia up to 41%. The presence of Ole e 1‐ and Ole e 4‐like allergens in E. angustifolia extract was confirmed by enzyme‐linked immunosorbent (ELISA) inhibition assays. Nasal challenge with E. angustifolia was positive in three of six patients with positive skin test to both pollens and negative in five patients with positive skin test only to O. europaea.
Conclusions: This study confirms that E. angustifolia is capable of sensitizing individuals in Madrid. A minimal‐to‐moderate cross‐reactivity with olive pollen was established, suggesting some cross‐reactivity but not excluding co‐sensitization. |
| doi_str_mv | 10.1111/j.1398-9995.2004.00530.x |
| format | Article |
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Methods: A total of 134 patients with rhinoconjunctivitis and/or asthma were studied. Its allergenicity, cross‐reactivity with olive pollen and the presence of Ole e 1 and Ole e 4‐like molecules were evaluated.
Results: Eleagnus angustifolia pollen was detected from May to June. Seventy‐three of 134 (30.5%) had positive skin test to E. angustifolia, all of them were positive to olive. There was a good correlation between specific immunoglobulin (Ig)E levels to E. angustifolia and Olea europaea (r = 0.77, P = 0.002). Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS‐PAGE) immunoblots revealed major IgE‐binding bands in the E. angustifolia extract of 43 and 63.7 kDa. The E. angustifolia extract was not able to inhibit olive, whereas O. europaea inhibited E. angustifolia up to 41%. The presence of Ole e 1‐ and Ole e 4‐like allergens in E. angustifolia extract was confirmed by enzyme‐linked immunosorbent (ELISA) inhibition assays. Nasal challenge with E. angustifolia was positive in three of six patients with positive skin test to both pollens and negative in five patients with positive skin test only to O. europaea.
Conclusions: This study confirms that E. angustifolia is capable of sensitizing individuals in Madrid. A minimal‐to‐moderate cross‐reactivity with olive pollen was established, suggesting some cross‐reactivity but not excluding co‐sensitization.</description><identifier>ISSN: 0105-4538</identifier><identifier>EISSN: 1398-9995</identifier><identifier>DOI: 10.1111/j.1398-9995.2004.00530.x</identifier><identifier>PMID: 15461599</identifier><identifier>CODEN: LLRGDY</identifier><language>eng</language><publisher>Oxford, UK: Munksgaard International Publishers</publisher><subject>Air Pollution ; allergens ; Allergens - immunology ; Allergic diseases ; Allergies ; Antigens, Plant ; Asthma - epidemiology ; Asthma - immunology ; Biological and medical sciences ; Conjunctivitis - epidemiology ; Conjunctivitis - immunology ; Cross Reactions - immunology ; cross‐reactivity ; Diagnostic tests ; Elaeagnaceae - immunology ; Eleagnus angustifolia ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Humans ; Hypersensitivity - epidemiology ; Hypersensitivity - immunology ; Immunopathology ; Medical sciences ; Olea - immunology ; Olives ; Plant Proteins - immunology ; Pollen ; Pollen - immunology ; Prevalence ; Rhinitis - epidemiology ; Rhinitis - immunology ; Russian olive ; Skin Tests ; Spain</subject><ispartof>Allergy (Copenhagen), 2004-11, Vol.59 (11), p.1181-1186</ispartof><rights>2004 INIST-CNRS</rights><rights>Copyright 2004 Blackwell Munksgaard</rights><rights>2004 Blackwell Munksgaard</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4210-b5a3cdb9315a6a373a367acec824f2b3b4d8ec59b0f5c427882039570b40ba5c3</citedby><cites>FETCH-LOGICAL-c4210-b5a3cdb9315a6a373a367acec824f2b3b4d8ec59b0f5c427882039570b40ba5c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1398-9995.2004.00530.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1398-9995.2004.00530.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,1433,27924,27925,45574,45575,46409,46833</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16170430$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15461599$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sastre, J.</creatorcontrib><creatorcontrib>Lluch‐Bernal, M.</creatorcontrib><creatorcontrib>Bustillo, A. M. G.</creatorcontrib><creatorcontrib>Carnés, J.</creatorcontrib><creatorcontrib>Marañón, F.</creatorcontrib><creatorcontrib>Casanovas, M.</creatorcontrib><creatorcontrib>Fernández‐Caldas, E.</creatorcontrib><title>Allergenicity and cross‐reactivity of Russian olive pollen (Eleagnus angustifolia)</title><title>Allergy (Copenhagen)</title><addtitle>Allergy</addtitle><description>Background: The purposes of this study were: to determine the prevalence of sensitization and immunochemical characterization of Eleagnus angustifolia pollen (Russian olive) that belongs to the family Eleagnaceae.
Methods: A total of 134 patients with rhinoconjunctivitis and/or asthma were studied. Its allergenicity, cross‐reactivity with olive pollen and the presence of Ole e 1 and Ole e 4‐like molecules were evaluated.
Results: Eleagnus angustifolia pollen was detected from May to June. Seventy‐three of 134 (30.5%) had positive skin test to E. angustifolia, all of them were positive to olive. There was a good correlation between specific immunoglobulin (Ig)E levels to E. angustifolia and Olea europaea (r = 0.77, P = 0.002). Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS‐PAGE) immunoblots revealed major IgE‐binding bands in the E. angustifolia extract of 43 and 63.7 kDa. The E. angustifolia extract was not able to inhibit olive, whereas O. europaea inhibited E. angustifolia up to 41%. The presence of Ole e 1‐ and Ole e 4‐like allergens in E. angustifolia extract was confirmed by enzyme‐linked immunosorbent (ELISA) inhibition assays. Nasal challenge with E. angustifolia was positive in three of six patients with positive skin test to both pollens and negative in five patients with positive skin test only to O. europaea.
Conclusions: This study confirms that E. angustifolia is capable of sensitizing individuals in Madrid. A minimal‐to‐moderate cross‐reactivity with olive pollen was established, suggesting some cross‐reactivity but not excluding co‐sensitization.</description><subject>Air Pollution</subject><subject>allergens</subject><subject>Allergens - immunology</subject><subject>Allergic diseases</subject><subject>Allergies</subject><subject>Antigens, Plant</subject><subject>Asthma - epidemiology</subject><subject>Asthma - immunology</subject><subject>Biological and medical sciences</subject><subject>Conjunctivitis - epidemiology</subject><subject>Conjunctivitis - immunology</subject><subject>Cross Reactions - immunology</subject><subject>cross‐reactivity</subject><subject>Diagnostic tests</subject><subject>Elaeagnaceae - immunology</subject><subject>Eleagnus angustifolia</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>Humans</subject><subject>Hypersensitivity - epidemiology</subject><subject>Hypersensitivity - immunology</subject><subject>Immunopathology</subject><subject>Medical sciences</subject><subject>Olea - immunology</subject><subject>Olives</subject><subject>Plant Proteins - immunology</subject><subject>Pollen</subject><subject>Pollen - immunology</subject><subject>Prevalence</subject><subject>Rhinitis - epidemiology</subject><subject>Rhinitis - immunology</subject><subject>Russian olive</subject><subject>Skin Tests</subject><subject>Spain</subject><issn>0105-4538</issn><issn>1398-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkN1KwzAUx4Mobn68ghRB0IvWk6ZpG_BmjPkBBUHmdUizdGR07Uzaud35CD6jT2K6FXdrbhJyfv9zkh9CHoYAu3W_CDBhqc8Yo0EIEAUAlECwOULDv8IxGgIG6keUpAN0Zu0CAJKQwSkaYBrFmDI2RNNRWSozV5WWutl6opp50tTW_nx9GyVko9fddV14b621WlReXeq18la1i1Xe7aRUYl611gXnrW104cri7gKdFKK06rLfz9H742Q6fvaz16eX8SjzZRRi8HMqiJzljGAqYkESIkicCKlkGkZFmJM8mqVKUpZDQV0iSdMQCKMJ5BHkgkpyjq73fVem_miVbfiibk3lRnLMYoZTSIiD0j20-5dRBV8ZvRRmyzHwziZf8E4a76Txzibf2eQbF73q-7f5Us0OwV6fA256QFgpysKISmp74GKcQETAcQ977lOXavvvB_BRlrkD-QUdw5D5</recordid><startdate>200411</startdate><enddate>200411</enddate><creator>Sastre, J.</creator><creator>Lluch‐Bernal, M.</creator><creator>Bustillo, A. M. G.</creator><creator>Carnés, J.</creator><creator>Marañón, F.</creator><creator>Casanovas, M.</creator><creator>Fernández‐Caldas, E.</creator><general>Munksgaard International Publishers</general><general>Blackwell</general><general>Blackwell Publishing Ltd</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope></search><sort><creationdate>200411</creationdate><title>Allergenicity and cross‐reactivity of Russian olive pollen (Eleagnus angustifolia)</title><author>Sastre, J. ; Lluch‐Bernal, M. ; Bustillo, A. M. G. ; Carnés, J. ; Marañón, F. ; Casanovas, M. ; Fernández‐Caldas, E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4210-b5a3cdb9315a6a373a367acec824f2b3b4d8ec59b0f5c427882039570b40ba5c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Air Pollution</topic><topic>allergens</topic><topic>Allergens - immunology</topic><topic>Allergic diseases</topic><topic>Allergies</topic><topic>Antigens, Plant</topic><topic>Asthma - epidemiology</topic><topic>Asthma - immunology</topic><topic>Biological and medical sciences</topic><topic>Conjunctivitis - epidemiology</topic><topic>Conjunctivitis - immunology</topic><topic>Cross Reactions - immunology</topic><topic>cross‐reactivity</topic><topic>Diagnostic tests</topic><topic>Elaeagnaceae - immunology</topic><topic>Eleagnus angustifolia</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>Humans</topic><topic>Hypersensitivity - epidemiology</topic><topic>Hypersensitivity - immunology</topic><topic>Immunopathology</topic><topic>Medical sciences</topic><topic>Olea - immunology</topic><topic>Olives</topic><topic>Plant Proteins - immunology</topic><topic>Pollen</topic><topic>Pollen - immunology</topic><topic>Prevalence</topic><topic>Rhinitis - epidemiology</topic><topic>Rhinitis - immunology</topic><topic>Russian olive</topic><topic>Skin Tests</topic><topic>Spain</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sastre, J.</creatorcontrib><creatorcontrib>Lluch‐Bernal, M.</creatorcontrib><creatorcontrib>Bustillo, A. M. G.</creatorcontrib><creatorcontrib>Carnés, J.</creatorcontrib><creatorcontrib>Marañón, F.</creatorcontrib><creatorcontrib>Casanovas, M.</creatorcontrib><creatorcontrib>Fernández‐Caldas, E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Allergy (Copenhagen)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sastre, J.</au><au>Lluch‐Bernal, M.</au><au>Bustillo, A. M. G.</au><au>Carnés, J.</au><au>Marañón, F.</au><au>Casanovas, M.</au><au>Fernández‐Caldas, E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Allergenicity and cross‐reactivity of Russian olive pollen (Eleagnus angustifolia)</atitle><jtitle>Allergy (Copenhagen)</jtitle><addtitle>Allergy</addtitle><date>2004-11</date><risdate>2004</risdate><volume>59</volume><issue>11</issue><spage>1181</spage><epage>1186</epage><pages>1181-1186</pages><issn>0105-4538</issn><eissn>1398-9995</eissn><coden>LLRGDY</coden><abstract>Background: The purposes of this study were: to determine the prevalence of sensitization and immunochemical characterization of Eleagnus angustifolia pollen (Russian olive) that belongs to the family Eleagnaceae.
Methods: A total of 134 patients with rhinoconjunctivitis and/or asthma were studied. Its allergenicity, cross‐reactivity with olive pollen and the presence of Ole e 1 and Ole e 4‐like molecules were evaluated.
Results: Eleagnus angustifolia pollen was detected from May to June. Seventy‐three of 134 (30.5%) had positive skin test to E. angustifolia, all of them were positive to olive. There was a good correlation between specific immunoglobulin (Ig)E levels to E. angustifolia and Olea europaea (r = 0.77, P = 0.002). Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS‐PAGE) immunoblots revealed major IgE‐binding bands in the E. angustifolia extract of 43 and 63.7 kDa. The E. angustifolia extract was not able to inhibit olive, whereas O. europaea inhibited E. angustifolia up to 41%. The presence of Ole e 1‐ and Ole e 4‐like allergens in E. angustifolia extract was confirmed by enzyme‐linked immunosorbent (ELISA) inhibition assays. Nasal challenge with E. angustifolia was positive in three of six patients with positive skin test to both pollens and negative in five patients with positive skin test only to O. europaea.
Conclusions: This study confirms that E. angustifolia is capable of sensitizing individuals in Madrid. A minimal‐to‐moderate cross‐reactivity with olive pollen was established, suggesting some cross‐reactivity but not excluding co‐sensitization.</abstract><cop>Oxford, UK</cop><pub>Munksgaard International Publishers</pub><pmid>15461599</pmid><doi>10.1111/j.1398-9995.2004.00530.x</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Free Content; Access via Wiley Online Library; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Air Pollution allergens Allergens - immunology Allergic diseases Allergies Antigens, Plant Asthma - epidemiology Asthma - immunology Biological and medical sciences Conjunctivitis - epidemiology Conjunctivitis - immunology Cross Reactions - immunology cross‐reactivity Diagnostic tests Elaeagnaceae - immunology Eleagnus angustifolia Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Hypersensitivity - epidemiology Hypersensitivity - immunology Immunopathology Medical sciences Olea - immunology Olives Plant Proteins - immunology Pollen Pollen - immunology Prevalence Rhinitis - epidemiology Rhinitis - immunology Russian olive Skin Tests Spain |
| title | Allergenicity and cross‐reactivity of Russian olive pollen (Eleagnus angustifolia) |
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