Paclitaxel given by a weekly 1-h infusion in advanced esophageal cancer

Background: The purpose of the study was to evaluate the efficacy of weekly paclitaxel (Taxol) in advanced esophageal cancer. Patients and methods: One hundred and two patients with advanced esophageal cancer were treated with paclitaxel 80 mg/m2 weekly over a 1-h infusion. One cycle was defined as...

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Veröffentlicht in:	Annals of oncology 2007-05, Vol.18 (5), p.898-902
Hauptverfasser:	Ilson, DH, Wadleigh, RG, Leichman, LP, Kelsen, DP
Format:	Artikel
Sprache:	eng
Schlagworte:	adenocarcinoma Adenocarcinoma - drug therapy Adenocarcinoma - pathology Adult Aged Aged, 80 and over Antineoplastic agents Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Agents, Phytogenic - adverse effects Arthralgia - chemically induced Biological and medical sciences Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - pathology Drug Administration Schedule esophageal cancer Esophageal Neoplasms - drug therapy Esophageal Neoplasms - pathology Esophagus Female Follow-Up Studies Gastroenterology. Liver. Pancreas. Abdomen Humans Infusions, Intravenous Male Medical sciences Middle Aged Neutropenia - chemically induced Paclitaxel - administration & dosage Paclitaxel - adverse effects Pharmacology. Drug treatments squamous cell carcinoma Survival Analysis Thrombocytopenia - chemically induced Time Factors Treatment Outcome Tumors weekly paclitaxel
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