Prevention of chemotherapy-induced menopause by temporary ovarian suppression with goserelin in young, early breast cancer patients

Background: Standard methods to prevent chemotherapy-induced early menopause in young, breast cancer patients are unavailable to date. Preclinical data has suggested that luteinising hormone-releasing hormone (LH-RH) analogs given during treatment can decrease the gonado-toxicity induced by chemothe...

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Veröffentlicht in:	Annals of oncology 2006-01, Vol.17 (1), p.74-78
Hauptverfasser:	Del Mastro, L., Catzeddu, T., Boni, L., Bell, C., Sertoli, M. R., Bighin, C., Clavarezza, M., Testa, D., Venturini, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic agents Antineoplastic Agents, Hormonal - therapeutic use Antineoplastic Combined Chemotherapy Protocols - adverse effects Biological and medical sciences breast cancer Breast Neoplasms - blood Breast Neoplasms - drug therapy Cyclophosphamide - adverse effects Cytarabine - adverse effects early menopause Epirubicin - adverse effects Estradiol - blood Female fertility preservation Follicle Stimulating Hormone - blood Follicle Stimulating Hormone - metabolism Goserelin - therapeutic use Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Menopause - drug effects Menopause, Premature Menstrual Cycle Middle Aged Ovary - drug effects Pharmacology. Drug treatments Premenopause - drug effects Prospective Studies Tumors
Online-Zugang:	Volltext
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