Abraxane®, a novel Cremophor®-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer

Background: Abraxane® (ABI-007) is a novel 130-nm, albumin-bound (nab™) particle form of paclitaxel designed to utilize endogenous albumin pathways to increase intratumor concentrations of the active drug. This multicenter phase II study was designed to evaluate the efficacy and safety of Abraxane 2...

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Veröffentlicht in:	Annals of oncology 2006-08, Vol.17 (8), p.1263-1268
Hauptverfasser:	Green, M. R., Manikhas, G. M., Orlov, S., Afanasyev, B., Makhson, A. M., Bhar, P., Hawkins, M. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	ABI-007 Adult Aged Albumin-Bound Paclitaxel Albumins - adverse effects Albumins - therapeutic use Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - mortality Female Humans Lung Neoplasms - drug therapy Lung Neoplasms - mortality Male Middle Aged nab nab-paclitaxel nanoparticle Paclitaxel - adverse effects Paclitaxel - therapeutic use Treatment Outcome
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