Implantable Systems for Stress Urinary Incontinence
Stress urinary incontinence (SUI), the involuntary urine leakage due to failure of the urethral closure mechanism, is a global health challenge with substantial human suffering and socioeconomic costs. Approximately 167 million male and female patients are predicted to suffer from SUI in 2018, world...
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| Veröffentlicht in: | Annals of biomedical engineering 2017-12, Vol.45 (12), p.2717-2732 |
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| creator | Al Adem, Kenana M. Bawazir, Sarah S. Hassen, Waleed A. Khandoker, Ahsan H. Khalaf, Kinda McGloughlin, Tim Stefanini, Cesare |
| description | Stress urinary incontinence (SUI), the involuntary urine leakage due to failure of the urethral closure mechanism, is a global health challenge with substantial human suffering and socioeconomic costs. Approximately 167 million male and female patients are predicted to suffer from SUI in 2018, worldwide. A wide range of surgical interventions are available for the treatment of SUI. Severe cases, however, usually require the implantation of artificial urinary sphincter devices. This review comparatively presents and analyzes the working principles, as well as the challenges, associated with the current implantable SUI systems in clinical use. These include slings, urethral bulking agents, artificial urinary sphincters, and adjustable continence devices. It further reports on recent research progress and state-of-the-art in the field of SUI implants, including an original approach proposed by the authors with a pressure feedback sensory mechanism. The new emerging field of artificial muscle devices, including electroactive polymers, provides a promising innovative solution for replacing the weakened urethral sphincter in SUI patients. |
| doi_str_mv | 10.1007/s10439-017-1939-9 |
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Approximately 167 million male and female patients are predicted to suffer from SUI in 2018, worldwide. A wide range of surgical interventions are available for the treatment of SUI. Severe cases, however, usually require the implantation of artificial urinary sphincter devices. This review comparatively presents and analyzes the working principles, as well as the challenges, associated with the current implantable SUI systems in clinical use. These include slings, urethral bulking agents, artificial urinary sphincters, and adjustable continence devices. It further reports on recent research progress and state-of-the-art in the field of SUI implants, including an original approach proposed by the authors with a pressure feedback sensory mechanism. The new emerging field of artificial muscle devices, including electroactive polymers, provides a promising innovative solution for replacing the weakened urethral sphincter in SUI patients.</description><identifier>ISSN: 0090-6964</identifier><identifier>EISSN: 1573-9686</identifier><identifier>DOI: 10.1007/s10439-017-1939-9</identifier><identifier>PMID: 29022114</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Biochemistry ; Biological and Medical Physics ; Biomedical and Life Sciences ; Biomedical Engineering and Bioengineering ; Biomedicine ; Biophysics ; Bioprosthesis ; Classical Mechanics ; Electroactive polymers ; Equipment Failure Analysis ; Global health ; Humans ; Implantation ; Patients ; Polymers ; Prostheses and Implants ; Prosthesis Design - methods ; Sphincter ; Suburethral Slings ; Surgical implants ; Treatment Outcome ; Urinary incontinence ; Urinary Incontinence, Stress - diagnosis ; Urinary Incontinence, Stress - physiopathology ; Urinary Incontinence, Stress - therapy ; Urinary Sphincter, Artificial ; Urine</subject><ispartof>Annals of biomedical engineering, 2017-12, Vol.45 (12), p.2717-2732</ispartof><rights>Biomedical Engineering Society 2017</rights><rights>Annals of Biomedical Engineering is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-e3ba7a5a3dd1d09124c6b5ec627fa82469dbc458b1a2b0e58facb0e25796c22f3</citedby><cites>FETCH-LOGICAL-c339t-e3ba7a5a3dd1d09124c6b5ec627fa82469dbc458b1a2b0e58facb0e25796c22f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10439-017-1939-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10439-017-1939-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29022114$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Al Adem, Kenana M.</creatorcontrib><creatorcontrib>Bawazir, Sarah S.</creatorcontrib><creatorcontrib>Hassen, Waleed A.</creatorcontrib><creatorcontrib>Khandoker, Ahsan H.</creatorcontrib><creatorcontrib>Khalaf, Kinda</creatorcontrib><creatorcontrib>McGloughlin, Tim</creatorcontrib><creatorcontrib>Stefanini, Cesare</creatorcontrib><title>Implantable Systems for Stress Urinary Incontinence</title><title>Annals of biomedical engineering</title><addtitle>Ann Biomed Eng</addtitle><addtitle>Ann Biomed Eng</addtitle><description>Stress urinary incontinence (SUI), the involuntary urine leakage due to failure of the urethral closure mechanism, is a global health challenge with substantial human suffering and socioeconomic costs. Approximately 167 million male and female patients are predicted to suffer from SUI in 2018, worldwide. A wide range of surgical interventions are available for the treatment of SUI. Severe cases, however, usually require the implantation of artificial urinary sphincter devices. This review comparatively presents and analyzes the working principles, as well as the challenges, associated with the current implantable SUI systems in clinical use. These include slings, urethral bulking agents, artificial urinary sphincters, and adjustable continence devices. It further reports on recent research progress and state-of-the-art in the field of SUI implants, including an original approach proposed by the authors with a pressure feedback sensory mechanism. The new emerging field of artificial muscle devices, including electroactive polymers, provides a promising innovative solution for replacing the weakened urethral sphincter in SUI patients.</description><subject>Biochemistry</subject><subject>Biological and Medical Physics</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Biomedicine</subject><subject>Biophysics</subject><subject>Bioprosthesis</subject><subject>Classical Mechanics</subject><subject>Electroactive polymers</subject><subject>Equipment Failure Analysis</subject><subject>Global health</subject><subject>Humans</subject><subject>Implantation</subject><subject>Patients</subject><subject>Polymers</subject><subject>Prostheses and Implants</subject><subject>Prosthesis Design - methods</subject><subject>Sphincter</subject><subject>Suburethral Slings</subject><subject>Surgical implants</subject><subject>Treatment Outcome</subject><subject>Urinary incontinence</subject><subject>Urinary Incontinence, Stress - diagnosis</subject><subject>Urinary Incontinence, Stress - physiopathology</subject><subject>Urinary Incontinence, Stress - therapy</subject><subject>Urinary Sphincter, Artificial</subject><subject>Urine</subject><issn>0090-6964</issn><issn>1573-9686</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kEtLw0AQxxdRbK1-AC8S8Byd2VeyRyk-CgUPtedls9lIS7Opu8mh394tqeLF0wzM_zH8CLlFeECA4jEicKZywCJHlRZ1RqYoCpYrWcpzMgVQkEsl-YRcxbgFQCyZuCQTqoBSRD4lbNHud8b3ptq5bHWIvWtj1nQhW_XBxZitw8abcMgW3na-33jnrbsmF43ZRXdzmjOyfnn-mL_ly_fXxfxpmVvGVJ87VpnCCMPqGmtQSLmVlXBW0qIxJeVS1ZXloqzQ0AqcKBtj06SiUNJS2rAZuR9z96H7Glzs9bYbgk-VGpUUwKEsMalwVNnQxRhco_dh06afNYI-YtIjJp0w6SMmrZLn7pQ8VK2rfx0_XJKAjoKYTv7ThT_V_6Z-A8ykch0</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Al Adem, Kenana 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Systems for Stress Urinary Incontinence</title><author>Al Adem, Kenana M. ; Bawazir, Sarah S. ; Hassen, Waleed A. ; Khandoker, Ahsan H. ; Khalaf, Kinda ; McGloughlin, Tim ; Stefanini, Cesare</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-e3ba7a5a3dd1d09124c6b5ec627fa82469dbc458b1a2b0e58facb0e25796c22f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Biochemistry</topic><topic>Biological and Medical Physics</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedical Engineering and Bioengineering</topic><topic>Biomedicine</topic><topic>Biophysics</topic><topic>Bioprosthesis</topic><topic>Classical Mechanics</topic><topic>Electroactive polymers</topic><topic>Equipment Failure Analysis</topic><topic>Global health</topic><topic>Humans</topic><topic>Implantation</topic><topic>Patients</topic><topic>Polymers</topic><topic>Prostheses and Implants</topic><topic>Prosthesis Design - methods</topic><topic>Sphincter</topic><topic>Suburethral Slings</topic><topic>Surgical implants</topic><topic>Treatment Outcome</topic><topic>Urinary incontinence</topic><topic>Urinary Incontinence, Stress - diagnosis</topic><topic>Urinary Incontinence, Stress - physiopathology</topic><topic>Urinary Incontinence, Stress - therapy</topic><topic>Urinary Sphincter, Artificial</topic><topic>Urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Al Adem, Kenana M.</creatorcontrib><creatorcontrib>Bawazir, Sarah S.</creatorcontrib><creatorcontrib>Hassen, Waleed A.</creatorcontrib><creatorcontrib>Khandoker, Ahsan H.</creatorcontrib><creatorcontrib>Khalaf, Kinda</creatorcontrib><creatorcontrib>McGloughlin, Tim</creatorcontrib><creatorcontrib>Stefanini, Cesare</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE 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Adem, Kenana M.</au><au>Bawazir, Sarah S.</au><au>Hassen, Waleed A.</au><au>Khandoker, Ahsan H.</au><au>Khalaf, Kinda</au><au>McGloughlin, Tim</au><au>Stefanini, Cesare</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Implantable Systems for Stress Urinary Incontinence</atitle><jtitle>Annals of biomedical engineering</jtitle><stitle>Ann Biomed Eng</stitle><addtitle>Ann Biomed Eng</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>45</volume><issue>12</issue><spage>2717</spage><epage>2732</epage><pages>2717-2732</pages><issn>0090-6964</issn><eissn>1573-9686</eissn><abstract>Stress urinary incontinence (SUI), the involuntary urine leakage due to failure of the urethral closure mechanism, is a global health challenge with substantial human suffering and socioeconomic costs. Approximately 167 million male and female patients are predicted to suffer from SUI in 2018, worldwide. A wide range of surgical interventions are available for the treatment of SUI. Severe cases, however, usually require the implantation of artificial urinary sphincter devices. This review comparatively presents and analyzes the working principles, as well as the challenges, associated with the current implantable SUI systems in clinical use. These include slings, urethral bulking agents, artificial urinary sphincters, and adjustable continence devices. It further reports on recent research progress and state-of-the-art in the field of SUI implants, including an original approach proposed by the authors with a pressure feedback sensory mechanism. The new emerging field of artificial muscle devices, including electroactive polymers, provides a promising innovative solution for replacing the weakened urethral sphincter in SUI patients.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>29022114</pmid><doi>10.1007/s10439-017-1939-9</doi><tpages>16</tpages></addata></record> |
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| subjects | Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Biophysics Bioprosthesis Classical Mechanics Electroactive polymers Equipment Failure Analysis Global health Humans Implantation Patients Polymers Prostheses and Implants Prosthesis Design - methods Sphincter Suburethral Slings Surgical implants Treatment Outcome Urinary incontinence Urinary Incontinence, Stress - diagnosis Urinary Incontinence, Stress - physiopathology Urinary Incontinence, Stress - therapy Urinary Sphincter, Artificial Urine |
| title | Implantable Systems for Stress Urinary Incontinence |
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