A systematic review and meta-analysis of the effects of isoflavone formulations against estrogen-deficient bone resorption in peri- and postmenopausal women

Age-related estrogen deficiency leads to accelerated bone resorption. There is evidence that, through selective estrogen receptor modulation, isoflavones may exert beneficial effects against estrogen-deficient bone loss. Isoflavone aglycones show higher bioavailability than their glycosidic counterp...

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Veröffentlicht in:	The American journal of clinical nutrition 2017-09, Vol.106 (3), p.801-811
Hauptverfasser:	Lambert, Max Norman Tandrup, Hu, Lin Meng, Jeppesen, Per Bendix
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aglycones Bioavailability Biological Availability bone Bone and Bones - drug effects Bone and Bones - metabolism Bone density Bone Density - drug effects Bone Density Conservation Agents - pharmacology Bone Density Conservation Agents - therapeutic use Bone loss Bone mineral density Bone resorption Bone Resorption - etiology Bone Resorption - metabolism Bone Resorption - prevention & control estrogen deficiency Estrogens Estrogens - deficiency Female Femur Formulations Glycosides Glycosides - pharmacology Glycosides - therapeutic use Humans isoflavone Isoflavones Isoflavones - pharmacology Isoflavones - therapeutic use Menopause Meta-analysis Middle Aged osteopenia osteoporosis Osteoporosis - etiology Osteoporosis - metabolism Osteoporosis - pathology Osteoporosis - prevention & control Phytotherapy Plant Extracts - pharmacology Plant Extracts - therapeutic use Post-menopause Spine Spine (lumbar) Systematic review Womens health
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