MOHS micrographic surgery for treating erosive adenoma of the nipple: a case report and review of the literature

Background Erosive adenoma of the nipple (EAN) is a benign condition that involves major ducts of the nipple. Its clinical presentation may resemble other disorders. Complete removal of the nipple is often suggested because of frequent relapse. However, adverse cosmetic and functional results have p...

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Veröffentlicht in:International journal of dermatology 2017-12, Vol.56 (12), p.1451-1454
Hauptverfasser: Barco, Israel, Vidal, MCarmen, Fraile, Manel, Masferrer, Emili, Barco, Leo, Barco, Didac, Baez, Cinthya J., Giménez, Nuria, Pessarrodona, Antoni, García‐Fernández, Antonio
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container_end_page 1454
container_issue 12
container_start_page 1451
container_title International journal of dermatology
container_volume 56
creator Barco, Israel
Vidal, MCarmen
Fraile, Manel
Masferrer, Emili
Barco, Leo
Barco, Didac
Baez, Cinthya J.
Giménez, Nuria
Pessarrodona, Antoni
García‐Fernández, Antonio
description Background Erosive adenoma of the nipple (EAN) is a benign condition that involves major ducts of the nipple. Its clinical presentation may resemble other disorders. Complete removal of the nipple is often suggested because of frequent relapse. However, adverse cosmetic and functional results have prompted clinicians to look for other more conservative options. Aims To present a case of EAN successfully treated using Mohs micrographic surgery (MMS) and summarize differential diagnosis and treatment. Materials and Methods A 40‐year‐old woman with EAN was diagnosed by immunohistochemical markers after clinical suspicion. We have reviewed other cases treated with MMS in the literature. Results In this patient, lesion size was 0.8 cm and the margin specimen was 1 × 0.9 × 0.2 cm, with EAN as histopathologic diagnosis. No atypia or malignancy was reported. Final esthetic outcome was reached with only one session, under local anesthesia and on an outpatient basis. Discussion Dermatologic lesions appearing on the nipple's surface should be closely followed. Paget's disease, carcinoma or proliferative lesions like EAN have to be considered, and such conditions require different surgical approaches. Traditional complete removal of the nipple is performed in many cases, but it may result in over‐treatment and unfavorable cosmetic outcome. MMS is frequently used in dermatologic surgery to treat malignant lesions with a high cure rate, avoiding excess tissue excision and leading to better patient satisfaction. Conclusion EAN can be successfully treated by minimal resection, especially if early diagnosis is done. MMS offers a better aesthetic outcome than traditional total excision.
doi_str_mv 10.1111/ijd.13747
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Its clinical presentation may resemble other disorders. Complete removal of the nipple is often suggested because of frequent relapse. However, adverse cosmetic and functional results have prompted clinicians to look for other more conservative options. Aims To present a case of EAN successfully treated using Mohs micrographic surgery (MMS) and summarize differential diagnosis and treatment. Materials and Methods A 40‐year‐old woman with EAN was diagnosed by immunohistochemical markers after clinical suspicion. We have reviewed other cases treated with MMS in the literature. Results In this patient, lesion size was 0.8 cm and the margin specimen was 1 × 0.9 × 0.2 cm, with EAN as histopathologic diagnosis. No atypia or malignancy was reported. Final esthetic outcome was reached with only one session, under local anesthesia and on an outpatient basis. Discussion Dermatologic lesions appearing on the nipple's surface should be closely followed. Paget's disease, carcinoma or proliferative lesions like EAN have to be considered, and such conditions require different surgical approaches. Traditional complete removal of the nipple is performed in many cases, but it may result in over‐treatment and unfavorable cosmetic outcome. MMS is frequently used in dermatologic surgery to treat malignant lesions with a high cure rate, avoiding excess tissue excision and leading to better patient satisfaction. Conclusion EAN can be successfully treated by minimal resection, especially if early diagnosis is done. MMS offers a better aesthetic outcome than traditional total excision.</description><identifier>ISSN: 0011-9059</identifier><identifier>EISSN: 1365-4632</identifier><identifier>DOI: 10.1111/ijd.13747</identifier><identifier>PMID: 28960299</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Adenoma ; Adenoma - surgery ; Adult ; Anesthesia ; Breast Neoplasms - surgery ; Case reports ; Diagnosis ; Differential diagnosis ; Experimental allergic neuritis ; Female ; Humans ; Lesions ; Literature reviews ; Malignancy ; Mohs Surgery ; Nipples - surgery ; Paget's disease ; Patient satisfaction ; Skin Neoplasms - surgery ; Surgery ; Tumors</subject><ispartof>International journal of dermatology, 2017-12, Vol.56 (12), p.1451-1454</ispartof><rights>2017</rights><rights>2017 The International Society of Dermatology.</rights><rights>International Journal of Dermatology © 2017 International Society of Dermatology</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3537-7a340b4430f42b63112a4f8da68d8376295d73d75a4c25ff35960dd64e0aff213</citedby><cites>FETCH-LOGICAL-c3537-7a340b4430f42b63112a4f8da68d8376295d73d75a4c25ff35960dd64e0aff213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fijd.13747$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fijd.13747$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28960299$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barco, Israel</creatorcontrib><creatorcontrib>Vidal, MCarmen</creatorcontrib><creatorcontrib>Fraile, Manel</creatorcontrib><creatorcontrib>Masferrer, Emili</creatorcontrib><creatorcontrib>Barco, Leo</creatorcontrib><creatorcontrib>Barco, Didac</creatorcontrib><creatorcontrib>Baez, Cinthya J.</creatorcontrib><creatorcontrib>Giménez, Nuria</creatorcontrib><creatorcontrib>Pessarrodona, Antoni</creatorcontrib><creatorcontrib>García‐Fernández, Antonio</creatorcontrib><title>MOHS micrographic surgery for treating erosive adenoma of the nipple: a case report and review of the literature</title><title>International journal of dermatology</title><addtitle>Int J Dermatol</addtitle><description>Background Erosive adenoma of the nipple (EAN) is a benign condition that involves major ducts of the nipple. Its clinical presentation may resemble other disorders. Complete removal of the nipple is often suggested because of frequent relapse. However, adverse cosmetic and functional results have prompted clinicians to look for other more conservative options. Aims To present a case of EAN successfully treated using Mohs micrographic surgery (MMS) and summarize differential diagnosis and treatment. Materials and Methods A 40‐year‐old woman with EAN was diagnosed by immunohistochemical markers after clinical suspicion. We have reviewed other cases treated with MMS in the literature. Results In this patient, lesion size was 0.8 cm and the margin specimen was 1 × 0.9 × 0.2 cm, with EAN as histopathologic diagnosis. No atypia or malignancy was reported. Final esthetic outcome was reached with only one session, under local anesthesia and on an outpatient basis. Discussion Dermatologic lesions appearing on the nipple's surface should be closely followed. Paget's disease, carcinoma or proliferative lesions like EAN have to be considered, and such conditions require different surgical approaches. Traditional complete removal of the nipple is performed in many cases, but it may result in over‐treatment and unfavorable cosmetic outcome. MMS is frequently used in dermatologic surgery to treat malignant lesions with a high cure rate, avoiding excess tissue excision and leading to better patient satisfaction. Conclusion EAN can be successfully treated by minimal resection, especially if early diagnosis is done. MMS offers a better aesthetic outcome than traditional total excision.</description><subject>Adenoma</subject><subject>Adenoma - surgery</subject><subject>Adult</subject><subject>Anesthesia</subject><subject>Breast Neoplasms - surgery</subject><subject>Case reports</subject><subject>Diagnosis</subject><subject>Differential diagnosis</subject><subject>Experimental allergic neuritis</subject><subject>Female</subject><subject>Humans</subject><subject>Lesions</subject><subject>Literature reviews</subject><subject>Malignancy</subject><subject>Mohs Surgery</subject><subject>Nipples - surgery</subject><subject>Paget's disease</subject><subject>Patient satisfaction</subject><subject>Skin Neoplasms - surgery</subject><subject>Surgery</subject><subject>Tumors</subject><issn>0011-9059</issn><issn>1365-4632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1PwkAQhjdGI4ge_ANmE08eCvvVlnoz-AEGw0E9N0t3Fpb0y90Wwr93teDNucxM8uSdzIPQNSVD6mtkNmpIeSziE9SnPAoDEXF2ivqEUBokJEx66MK5jV85o-Ic9dg4iQhLkj6q3xbTd1yYzFYrK-u1ybBr7QrsHuvK4saCbEy5wmArZ7aApYKyKiSuNG7WgEtT1zncY4kz6QBbqCvbYFkqP24N7I5cbhqwsmktXKIzLXMHV4c-QJ_PTx-TaTBfvMwmD_Mg4yGPg1hyQZZCcKIFW0acUiaFHisZjdWYxxFLQhVzFYdSZCzUmof-I6UiAURqzSgfoNsut7bVVwuuSTdVa0t_MqVJxEnICI09dddR_n_nLOi0tqaQdp9Skv64Tb3b9NetZ28Oie2yAPVHHmV6YNQBO5PD_v-kdPb62EV-Azq_grQ</recordid><startdate>201712</startdate><enddate>201712</enddate><creator>Barco, Israel</creator><creator>Vidal, MCarmen</creator><creator>Fraile, Manel</creator><creator>Masferrer, Emili</creator><creator>Barco, Leo</creator><creator>Barco, Didac</creator><creator>Baez, Cinthya J.</creator><creator>Giménez, Nuria</creator><creator>Pessarrodona, Antoni</creator><creator>García‐Fernández, Antonio</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U7</scope><scope>C1K</scope><scope>H94</scope></search><sort><creationdate>201712</creationdate><title>MOHS micrographic surgery for treating erosive adenoma of the nipple: a case report and review of the literature</title><author>Barco, Israel ; Vidal, MCarmen ; Fraile, Manel ; Masferrer, Emili ; Barco, Leo ; Barco, Didac ; Baez, Cinthya J. ; Giménez, Nuria ; Pessarrodona, Antoni ; García‐Fernández, Antonio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3537-7a340b4430f42b63112a4f8da68d8376295d73d75a4c25ff35960dd64e0aff213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adenoma</topic><topic>Adenoma - surgery</topic><topic>Adult</topic><topic>Anesthesia</topic><topic>Breast Neoplasms - surgery</topic><topic>Case reports</topic><topic>Diagnosis</topic><topic>Differential diagnosis</topic><topic>Experimental allergic neuritis</topic><topic>Female</topic><topic>Humans</topic><topic>Lesions</topic><topic>Literature reviews</topic><topic>Malignancy</topic><topic>Mohs Surgery</topic><topic>Nipples - surgery</topic><topic>Paget's disease</topic><topic>Patient satisfaction</topic><topic>Skin Neoplasms - surgery</topic><topic>Surgery</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barco, Israel</creatorcontrib><creatorcontrib>Vidal, MCarmen</creatorcontrib><creatorcontrib>Fraile, Manel</creatorcontrib><creatorcontrib>Masferrer, Emili</creatorcontrib><creatorcontrib>Barco, Leo</creatorcontrib><creatorcontrib>Barco, Didac</creatorcontrib><creatorcontrib>Baez, Cinthya J.</creatorcontrib><creatorcontrib>Giménez, Nuria</creatorcontrib><creatorcontrib>Pessarrodona, Antoni</creatorcontrib><creatorcontrib>García‐Fernández, Antonio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>International journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barco, Israel</au><au>Vidal, MCarmen</au><au>Fraile, Manel</au><au>Masferrer, Emili</au><au>Barco, Leo</au><au>Barco, Didac</au><au>Baez, Cinthya J.</au><au>Giménez, Nuria</au><au>Pessarrodona, Antoni</au><au>García‐Fernández, Antonio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MOHS micrographic surgery for treating erosive adenoma of the nipple: a case report and review of the literature</atitle><jtitle>International journal of dermatology</jtitle><addtitle>Int J Dermatol</addtitle><date>2017-12</date><risdate>2017</risdate><volume>56</volume><issue>12</issue><spage>1451</spage><epage>1454</epage><pages>1451-1454</pages><issn>0011-9059</issn><eissn>1365-4632</eissn><abstract>Background Erosive adenoma of the nipple (EAN) is a benign condition that involves major ducts of the nipple. Its clinical presentation may resemble other disorders. Complete removal of the nipple is often suggested because of frequent relapse. However, adverse cosmetic and functional results have prompted clinicians to look for other more conservative options. Aims To present a case of EAN successfully treated using Mohs micrographic surgery (MMS) and summarize differential diagnosis and treatment. Materials and Methods A 40‐year‐old woman with EAN was diagnosed by immunohistochemical markers after clinical suspicion. We have reviewed other cases treated with MMS in the literature. Results In this patient, lesion size was 0.8 cm and the margin specimen was 1 × 0.9 × 0.2 cm, with EAN as histopathologic diagnosis. No atypia or malignancy was reported. Final esthetic outcome was reached with only one session, under local anesthesia and on an outpatient basis. Discussion Dermatologic lesions appearing on the nipple's surface should be closely followed. Paget's disease, carcinoma or proliferative lesions like EAN have to be considered, and such conditions require different surgical approaches. Traditional complete removal of the nipple is performed in many cases, but it may result in over‐treatment and unfavorable cosmetic outcome. MMS is frequently used in dermatologic surgery to treat malignant lesions with a high cure rate, avoiding excess tissue excision and leading to better patient satisfaction. Conclusion EAN can be successfully treated by minimal resection, especially if early diagnosis is done. MMS offers a better aesthetic outcome than traditional total excision.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>28960299</pmid><doi>10.1111/ijd.13747</doi><tpages>4</tpages></addata></record>
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subjects Adenoma
Adenoma - surgery
Adult
Anesthesia
Breast Neoplasms - surgery
Case reports
Diagnosis
Differential diagnosis
Experimental allergic neuritis
Female
Humans
Lesions
Literature reviews
Malignancy
Mohs Surgery
Nipples - surgery
Paget's disease
Patient satisfaction
Skin Neoplasms - surgery
Surgery
Tumors
title MOHS micrographic surgery for treating erosive adenoma of the nipple: a case report and review of the literature
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