Lipid-Coated Gold Nanoparticles Functionalized by Folic Acid as Gene Vectors for Targeted Gene Delivery invitro and invivo

Lipid-based nanoparticles as gene vectors have attracted considerable attention for their high gene transfection efficiency and low cytotoxicity. In our previous work, we synthesized gold nanoparticles/dimethyldioctadecylammonium bromide (DODAB)/dioleoylphosphatidylethanolamine (DOPE) (GDD) as anion...

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Veröffentlicht in:	ChemMedChem 2017-11, Vol.12 (21), p.1768
Hauptverfasser:	Du, Baoji, Gu, Xiaoxiao, Han, Xu, Ding, Guanyu, Wang, Yuling, Li, Dan, Wang, Erkang, Wang, Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tissues Cytotoxicity Efficiency Folic acid Gene therapy Gene transfer Gold Lipids Nanoparticles pH effects Receptors Toxicity Transfection Tumor cells Vectors (Biology)
Online-Zugang:	Volltext
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