FUCA1 is induced by wild-type p53 and expressed at different levels in thyroid cancers depending on p53 status

Fucose residues of cell surface glycans, which play important roles in growth, invasion and metastasis, are added by fucosyltransferases (FUTs) and removed by α-L-fucosidases (FUCAs). By the differential display method, we isolated a 3' non-coding region of α-L-fucosidase-1 (FUCA1) (a gene codi...

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Veröffentlicht in:	International journal of oncology 2017-06, Vol.50 (6), p.2043-2048
Hauptverfasser:	Tsuchida, Nobuo, Ikeda, Masa-Aki, Ιshino, Υoshizumu, Grieco, Michele, Vecchio, Giancarlo
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-L-Fucosidase - genetics Apoptosis Bone cancer Breast cancer Cancer cells Carcinoma, Papillary - genetics Carcinoma, Papillary - pathology Care and treatment Cell growth Cell Line, Tumor Cloning Deoxyribonucleic acid DNA Female Fucose - metabolism Fucosyltransferases - genetics Gene Expression Regulation, Neoplastic Genes Genotype & phenotype Glycoproteins Humans Male Membrane filters Metastasis Mutation Neoplasm Metastasis Phosphorylation Proteins Thyroid cancer Thyroid Cancer, Papillary Thyroid Carcinoma, Anaplastic - genetics Thyroid Carcinoma, Anaplastic - pathology Thyroid Gland - metabolism Thyroid Gland - pathology Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Tissue Array Analysis Tumor Suppressor Protein p53 - genetics
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